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Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy

Patients with malignant tumors frequently suffer during disease progression from a syndrome referred to as cancer cachexia (CaCax): CaCax includes skeletal muscle atrophy and weakness, loss of bodyweight, and fat tissues. Currently, there are no FDA (Food and Drug Administration) approved treatments...

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Detalles Bibliográficos
Autores principales:	Adams, Volker, Gußen, Victoria, Zozulya, Sergey, Cruz, André, Moriscot, Anselmo, Linke, Axel, Labeit, Siegfried
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600862/ https://www.ncbi.nlm.nih.gov/pubmed/33050629 http://dx.doi.org/10.3390/cells9102272

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