An Electrophilic Deguelin Analogue Inhibits STAT3 Signaling in H-Ras-Transformed Human Mammary Epithelial Cells: The Cysteine 259 Residue as a Potential Target

Signal transducer and activator of transcription 3 (STAT3) is a point of convergence for numerous oncogenic signals that are often constitutively activated in many cancerous or transformed cells and some stromal cells in the tumor microenvironment. Persistent STAT3 activation in malignant cells stim...

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Detalles Bibliográficos
Autores principales: Hong, Sung-Jun, Kim, Jin-Tae, Kim, Su-Jung, Cho, Nam-Chul, Kim, Kyeojin, Lee, Seungbeom, Suh, Young-Ger, Cho, Kyung-Cho, Kim, Kwang Pyo, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600869/
https://www.ncbi.nlm.nih.gov/pubmed/33053804
http://dx.doi.org/10.3390/biomedicines8100407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600869/
https://www.ncbi.nlm.nih.gov/pubmed/33053804
http://dx.doi.org/10.3390/biomedicines8100407

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