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Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage

BRISC and BRCA1-A complex member 2 (Babam2) plays an essential role in promoting cell cycle progression and preventing cellular senescence. Babam2-deficient fibroblasts show proliferation defect and premature senescence compared with their wild-type (WT) counterpart. Pluripotent mouse embryonic stem...

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Detalles Bibliográficos
Autores principales: Chung, Cheuk Yiu Tenny, Lo, Paulisally Hau Yi, Lee, Kenneth Ka Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899/
https://www.ncbi.nlm.nih.gov/pubmed/33050379
http://dx.doi.org/10.3390/biomedicines8100397