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Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage
BRISC and BRCA1-A complex member 2 (Babam2) plays an essential role in promoting cell cycle progression and preventing cellular senescence. Babam2-deficient fibroblasts show proliferation defect and premature senescence compared with their wild-type (WT) counterpart. Pluripotent mouse embryonic stem...
Autores principales: | Chung, Cheuk Yiu Tenny, Lo, Paulisally Hau Yi, Lee, Kenneth Ka Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899/ https://www.ncbi.nlm.nih.gov/pubmed/33050379 http://dx.doi.org/10.3390/biomedicines8100397 |
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