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Sex-Specific Control of Muscle Mass: Elevated IGFBP Proteolysis and Reductions of IGF-1 Levels Are Associated with Substantial Loss of Carcass Weight in Male DU6PxIGFBP-2 Transgenic Mice

In farmed animals, carcass weight represents an important economic trait. Since we had demonstrated that IGFBP-2 represents a potent inhibitor of muscle accretion in inbred mice, we wanted to quantify the inhibitory effects of IGFBP-2 under conditions of elevated protein mass in growth selected non-...

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Detalles Bibliográficos
Autores principales:	Ohde, Daniela, Walz, Michael, Walz, Christina, Noce, Antonia, Brenmoehl, Julia, Langhammer, Martina, Hoeflich, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600981/ https://www.ncbi.nlm.nih.gov/pubmed/32993096 http://dx.doi.org/10.3390/cells9102174

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