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BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification
The field of breath analysis lacks a fully automated analysis platform that enforces machine learning good practice and enables clinicians and clinical researchers to rapidly and reproducibly discover metabolite patterns in diseases. We present BALSAM—a comprehensive web-platform to simplify and aut...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601018/ https://www.ncbi.nlm.nih.gov/pubmed/33023186 http://dx.doi.org/10.3390/metabo10100393 |
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author | Weber, Philipp Pauling, Josch Konstantin List, Markus Baumbach, Jan |
author_facet | Weber, Philipp Pauling, Josch Konstantin List, Markus Baumbach, Jan |
author_sort | Weber, Philipp |
collection | PubMed |
description | The field of breath analysis lacks a fully automated analysis platform that enforces machine learning good practice and enables clinicians and clinical researchers to rapidly and reproducibly discover metabolite patterns in diseases. We present BALSAM—a comprehensive web-platform to simplify and automate this process, offering features for preprocessing, peak detection, feature extraction, visualization and pattern discovery. Our main focus is on data from multi-capillary-column ion-mobility-spectrometry. While not limited to breath data, BALSAM was developed to increase consistency and robustness in the data analysis process of breath samples, aiming to expand the array of low cost molecular diagnostics in clinics. Our platform is freely available as a web-service and in form of a publicly available docker container. |
format | Online Article Text |
id | pubmed-7601018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76010182020-11-01 BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification Weber, Philipp Pauling, Josch Konstantin List, Markus Baumbach, Jan Metabolites Article The field of breath analysis lacks a fully automated analysis platform that enforces machine learning good practice and enables clinicians and clinical researchers to rapidly and reproducibly discover metabolite patterns in diseases. We present BALSAM—a comprehensive web-platform to simplify and automate this process, offering features for preprocessing, peak detection, feature extraction, visualization and pattern discovery. Our main focus is on data from multi-capillary-column ion-mobility-spectrometry. While not limited to breath data, BALSAM was developed to increase consistency and robustness in the data analysis process of breath samples, aiming to expand the array of low cost molecular diagnostics in clinics. Our platform is freely available as a web-service and in form of a publicly available docker container. MDPI 2020-10-02 /pmc/articles/PMC7601018/ /pubmed/33023186 http://dx.doi.org/10.3390/metabo10100393 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Weber, Philipp Pauling, Josch Konstantin List, Markus Baumbach, Jan BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification |
title | BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification |
title_full | BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification |
title_fullStr | BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification |
title_full_unstemmed | BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification |
title_short | BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification |
title_sort | balsam—an interactive online platform for breath analysis, visualization and classification |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601018/ https://www.ncbi.nlm.nih.gov/pubmed/33023186 http://dx.doi.org/10.3390/metabo10100393 |
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