Cargando…

Characterization of iRGD-Ligand Modified Arginine-Histidine-Rich Peptides for Nucleic Acid Therapeutics Delivery to αvβ3 Integrin-Expressing Cancer Cells

Efficient and specific delivery of nucleic acid (NA) therapeutics to tumor cells is extremely important for cancer gene therapy. Various therapeutic strategies include delivery of DNA-therapeutics such as immunostimulatory or suicide genes and delivery of siRNA-therapeutics able to silence expressio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Egorova, Anna, Selutin, Alexander, Maretina, Marianna, Selkov, Sergei, Baranov, Vladislav, Kiselev, Anton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601072/ https://www.ncbi.nlm.nih.gov/pubmed/33050526 http://dx.doi.org/10.3390/ph13100300

Ejemplares similares

Development of iRGD-Modified Peptide Carriers for Suicide Gene Therapy of Uterine Leiomyoma
por: Egorova, Anna, et al.
Publicado: (2021)

Polycondensed Peptide Carriers Modified with Cyclic RGD Ligand for Targeted Suicide Gene Delivery to Uterine Fibroid Cells
por: Egorova, Anna, et al.
Publicado: (2022)

iRGD-Targeted Peptide Nanoparticles for Anti-Angiogenic RNAi-Based Therapy of Endometriosis
por: Egorova, Anna, et al.
Publicado: (2023)

Peptide-Based Nanoparticles for αvβ3 Integrin-Targeted DNA Delivery to Cancer and Uterine Leiomyoma Cells
por: Egorova, Anna, et al.
Publicado: (2022)

Synergistic Anti-Angiogenic Effects Using Peptide-Based Combinatorial Delivery of siRNAs Targeting VEGFA, VEGFR1, and Endoglin Genes
por: Egorova, Anna A., et al.
Publicado: (2019)

Peptide Nanoparticle-Mediated Combinatorial Delivery of Cancer-Related siRNAs for Synergistic Anti-Proliferative Activity in Triple Negative Breast Cancer Cells
por: Egorova, Anna, et al.
Publicado: (2021)

Magnetic Nanoparticles as a Component of Peptide-Based DNA Delivery System for Suicide Gene Therapy of Uterine Leiomyoma
por: Shtykalova, Sofia, et al.
Publicado: (2022)

Evaluation of Mean Percentage of Full-Length SMN Transcripts as a Molecular Biomarker of Spinal Muscular Atrophy
por: Maretina, Marianna, et al.
Publicado: (2022)

Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles
por: D’Amore, Vincenzo Maria, et al.
Publicado: (2023)

An iRGD peptide conjugated heparin nanocarrier for gastric cancer therapy
por: Ai, Shichao, et al.
Publicado: (2018)

An iRGD Based Strategy to Study Electrochemically the Species Inside a Cell
por: Ning, Limin, et al.
Publicado: (2012)

Molecular Factors Involved in Spinal Muscular Atrophy Pathways as Possible Disease-modifying Candidates
por: Maretina, Marianna A., et al.
Publicado: (2018)

Enhanced Therapeutic Efficacy of iRGD-Conjugated Crosslinked Multilayer Liposomes for Drug Delivery
por: Liu, Yarong, et al.
Publicado: (2013)

sTRAIL-iRGD is a promising therapeutic agent for gastric cancer treatment
por: Huang, Ying, et al.
Publicado: (2017)

iRGD Peptide as a Tumor-Penetrating Enhancer for Tumor-Targeted Drug Delivery
por: Kang, Sujin, et al.
Publicado: (2020)

Dual Effect of Chemo-PDT with Tumor Targeting Nanoparticles Containing iRGD Peptide
por: Kim, Gye Lim, et al.
Publicado: (2023)

Anticancer activity of Pseudomonas aeruginosa derived peptide with iRGD in colon cancer therapy
por: Yaghoubi, Atieh, et al.
Publicado: (2023)

Click Chemistry for the Synthesis of RGD-Containing Integrin Ligands
por: Colombo, Matteo, et al.
Publicado: (2010)

iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer
por: Ding, Naiqing, et al.
Publicado: (2019)

Improved Anticancer Effect of Recombinant Protein izTRAIL Combined with Sorafenib and Peptide iRGD
por: Fadeev, Roman, et al.
Publicado: (2019)

Remarkable Boron Delivery Of iRGD-Modified Polymeric Nanoparticles For Boron Neutron Capture Therapy
por: Chen, Jiejian, et al.
Publicado: (2019)

Molecular Imaging of Steroid-Induced Osteonecrosis of the Femoral Head through iRGD-Targeted Microbubbles
por: Zhao, Ping, et al.
Publicado: (2022)

iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma
por: Dong, Yanbing, et al.
Publicado: (2023)

Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin upon Co-Administration with TP5-iRGD Peptide
por: E. M. Eid, Eltayeb, et al.
Publicado: (2019)

Co-administration of iRGD with peptide HPRP-A1 to improve anticancer activity and membrane penetrability
por: Hu, Cuihua, et al.
Publicado: (2018)

iRGD: A Promising Peptide for Cancer Imaging and a Potential Therapeutic Agent for Various Cancers
por: Zuo, Houdong
Publicado: (2019)

iRGD conjugated nimbolide liposomes protect against endotoxin induced acute respiratory distress syndrome
por: Pooladanda, Venkatesh, et al.
Publicado: (2021)

Combined Self-Assembled iRGD Polymersomes for Effective Targeted siRNA Anti-Tumor Therapy
por: Li, Dongying, et al.
Publicado: (2022)

Correction: iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma
por: Dong, Yanbing, et al.
Publicado: (2023)

The Antitumour Activity of a Curcumin and Piperine Loaded iRGD-Modified Liposome: In Vitro and In Vivo Evaluation
por: Wang, Yingzheng, et al.
Publicado: (2023)

Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus
por: Al-Zaher, Ahmed Abdullah, et al.
Publicado: (2018)

Modification of erythrocytes by internalizing Arg-Gly-Asp (iRGD) in boosting the curative effect of radiotherapy for gastric carcinoma
por: Zhou, Chong, et al.
Publicado: (2022)

Development of 2′-O-Methyl and LNA Antisense Oligonucleotides for SMN2 Splicing Correction in SMA Cells
por: Maretina, Marianna, et al.
Publicado: (2023)

The Effect of Superparamagnetic Iron Oxide with iRGD Peptide on the Labeling of Pancreatic Cancer Cells In Vitro: A Preliminary Study
por: Zuo, Hou Dong, et al.
Publicado: (2014)

Tumor-penetration and antitumor efficacy of cetuximab are enhanced by co-administered iRGD in a murine model of human NSCLC
por: Zhang, Yang, et al.
Publicado: (2016)

Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency
por: Bian, Xinyu, et al.
Publicado: (2016)

GSH-responsive SN38 dimer-loaded shape-transformable nanoparticles with iRGD for enhancing chemo-photodynamic therapy
por: Lin, Congcong, et al.
Publicado: (2020)

Bifunctional iRGD-anti-CD3 enhances antitumor potency of T cells by facilitating tumor infiltration and T-cell activation
por: Zhou, Shujuan, et al.
Publicado: (2021)

Effective Triple-Negative Breast Cancer Targeted Treatment Using iRGD-Modified RBC Membrane-Camouflaged Nanoparticles
por: Huang, Jingbin, et al.
Publicado: (2021)

A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins
por: Kapp, Tobias G., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1dp2naacgghv112259qqcnihl6