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Under-Replicated DNA: The Byproduct of Large Genomes?

SIMPLE SUMMARY: Higher eukaryotic cells frequently enter mitosis with a certain load of under-replicated DNA, also referred to as unreplicated DNA, due to incomplete genomic DNA replication during the previous S phase. Double replication fork stalling events, when two converging forks irreversibly s...

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Detalles Bibliográficos
Autores principales: Bertolin, Agustina P., Hoffmann, Jean-Sébastien, Gottifredi, Vanesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601121/
https://www.ncbi.nlm.nih.gov/pubmed/32992928
http://dx.doi.org/10.3390/cancers12102764