Papain-Like Proteases as Coronaviral Drug Targets: Current Inhibitors, Opportunities, and Limitations

Papain-like proteases (PLpro) of coronaviruses (CoVs) support viral reproduction and suppress the immune response of the host, which makes CoV PLpro perspective pharmaceutical targets. Their inhibition could both prevent viral replication and boost the immune system of the host, leading to the speed...

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Detalles Bibliográficos
Autores principales: Petushkova, Anastasiia I., Zamyatnin, Andrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601131/
https://www.ncbi.nlm.nih.gov/pubmed/32998368
http://dx.doi.org/10.3390/ph13100277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601131/
https://www.ncbi.nlm.nih.gov/pubmed/32998368
http://dx.doi.org/10.3390/ph13100277

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