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Development of Metronidazole Loaded Chitosan Nanoparticles Using QbD Approach—A Novel and Potential Antibacterial Formulation
The aim of this study was to design, optimize, and develop metronidazole (Met) loaded nanoparticles (MetNp) by employing quality-based design (QbD) as well as a risk assessment methodology. A fractional factorial design was used by selecting five independent variables viz., chitosan concentration, t...
Autores principales: | Sreeharsha, Nagaraja, Rajpoot, Kuldeep, Tekade, Muktika, Kalyane, Dnyaneshwar, Nair, Anroop B., Venugopala, Katharigatta N., Tekade, Rakesh K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601138/ https://www.ncbi.nlm.nih.gov/pubmed/32992903 http://dx.doi.org/10.3390/pharmaceutics12100920 |
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