Cargando…
Copper Complexes as Anticancer Agents Targeting Topoisomerases I and II
SIMPLE SUMMARY: Organometallics, such as copper compounds, are cancer chemotherapeutics used alone or in combination with other drugs. One small group of copper complexes exerts an effective inhibitory action on topoisomerases, which participate in the regulation of DNA topology. Copper complexes of...
Autores principales: | Molinaro, Caroline, Martoriati, Alain, Pelinski, Lydie, Cailliau, Katia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601307/ https://www.ncbi.nlm.nih.gov/pubmed/33027952 http://dx.doi.org/10.3390/cancers12102863 |
Ejemplares similares
-
A Novel Copper(II) Indenoisoquinoline Complex Inhibits Topoisomerase I, Induces G2 Phase Arrest, and Autophagy in Three Adenocarcinomas
por: Molinaro, Caroline, et al.
Publicado: (2022) -
Synthesis and Biological Activity of a New Indenoisoquinoline Copper Derivative as a Topoisomerase I Inhibitor
por: Molinaro, Caroline, et al.
Publicado: (2023) -
Proteins from the DNA Damage Response: Regulation, Dysfunction, and Anticancer Strategies
por: Molinaro, Caroline, et al.
Publicado: (2021) -
Effects of Ferrocenyl 4-(Imino)-1,4-Dihydro-quinolines on Xenopus laevis Prophase I - Arrested Oocytes: Survival and Hormonal-Induced M-Phase Entry
por: Marchand, Guillaume, et al.
Publicado: (2020) -
Another Facet to the Anticancer Response to Lamellarin D: Induction of Cellular Senescence through Inhibition of Topoisomerase I and Intracellular Ros Production
por: Ballot, Caroline, et al.
Publicado: (2014)