Cargando…
Conditioned Medium from Cells Overexpressing TDP-43 Alters the Metabolome of Recipient Cells
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the progressive death of both upper and lower motor neurons. The disease presents a poor prognosis, and patients usually die 2–5 years after the onset of symptoms. The hallmark of this disease is the presence of phosphoryla...
Autores principales: | Hergesheimer, Rudolf, Lanznaster, Débora, Bourgeais, Jérôme, Hérault, Olivier, Vourc’h, Patrick, Andres, Christian R., Corcia, Philippe, Blasco, Hélène |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601466/ https://www.ncbi.nlm.nih.gov/pubmed/33003404 http://dx.doi.org/10.3390/cells9102198 |
Ejemplares similares
-
TDP-43-Mediated Toxicity in HEK293T Cells: A Fast and Reproducible Protocol To Be Employed in the Search of New Therapeutic Options against Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2019) -
The debated toxic role of aggregated TDP-43 in amyotrophic lateral sclerosis: a resolution in sight?
por: Hergesheimer, Rudolf C, et al.
Publicado: (2019) -
Metabolomics: A Tool to Understand the Impact of Genetic Mutations in Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2020) -
Aβ1-42 and Tau as Potential Biomarkers for Diagnosis and Prognosis of Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2020) -
The Relevancy of Data Regarding the Metabolism of Iron to Our Understanding of Deregulated Mechanisms in ALS; Hypotheses and Pitfalls
por: Petillon, Camille, et al.
Publicado: (2019)