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Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy

While satisfactory results have been reported during short-to mid-term follow-up assessments of hemophilic patients who have undergone total knee arthroplasty (TKA), limited literature focusing on long-term survival following TKA exists to date. As part of this investigation, a consecutive series of...

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Autores principales: Bae, Jung-Kwon, Kim, Kang-Il, Lee, Sang-Hak, Yoo, Myung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601478/
https://www.ncbi.nlm.nih.gov/pubmed/33050640
http://dx.doi.org/10.3390/jcm9103247
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author Bae, Jung-Kwon
Kim, Kang-Il
Lee, Sang-Hak
Yoo, Myung-Chul
author_facet Bae, Jung-Kwon
Kim, Kang-Il
Lee, Sang-Hak
Yoo, Myung-Chul
author_sort Bae, Jung-Kwon
collection PubMed
description While satisfactory results have been reported during short-to mid-term follow-up assessments of hemophilic patients who have undergone total knee arthroplasty (TKA), limited literature focusing on long-term survival following TKA exists to date. As part of this investigation, a consecutive series of 78 TKAs in 56 patients with hemophilic arthropathy was reviewed. The mean patient age at the time of operation was 38.7 years old and the mean length of follow up was 10.2 years. Clinical and radiologic outcomes, quality of life, complications, and long-term survivorship of TKA were evaluated. At the latest point of follow up, the average American Knee Society (AKS) knee and function scores had improved from 32.1 to 85.7 points and 41.5 to 83.3 points, respectively. Moreover, the average range of motion (ROM) was significantly increased from 64.2° preoperatively to 84.2° postoperatively. The physical and mental Short Form-36 results were also significantly improved at the latest point of follow up. Postoperative complications appeared in 12 knees (15.4%). The readmission rate in the 30 days after discharge was 6.4%. Revision TKA was performed in three knees for periprosthetic joint infection (n = 2 knees) and tibial component loosening (n = 1 knee). The Kaplan–Meier 10- and 13-year prosthesis survival rates were 97.1% and 93.2%, respectively. The current study suggests that the mid-to long-term results of TKA in patients with hemophilic arthropathy are favorable, with successful long-term prosthesis survival achievable in most cases.
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spelling pubmed-76014782020-11-01 Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy Bae, Jung-Kwon Kim, Kang-Il Lee, Sang-Hak Yoo, Myung-Chul J Clin Med Article While satisfactory results have been reported during short-to mid-term follow-up assessments of hemophilic patients who have undergone total knee arthroplasty (TKA), limited literature focusing on long-term survival following TKA exists to date. As part of this investigation, a consecutive series of 78 TKAs in 56 patients with hemophilic arthropathy was reviewed. The mean patient age at the time of operation was 38.7 years old and the mean length of follow up was 10.2 years. Clinical and radiologic outcomes, quality of life, complications, and long-term survivorship of TKA were evaluated. At the latest point of follow up, the average American Knee Society (AKS) knee and function scores had improved from 32.1 to 85.7 points and 41.5 to 83.3 points, respectively. Moreover, the average range of motion (ROM) was significantly increased from 64.2° preoperatively to 84.2° postoperatively. The physical and mental Short Form-36 results were also significantly improved at the latest point of follow up. Postoperative complications appeared in 12 knees (15.4%). The readmission rate in the 30 days after discharge was 6.4%. Revision TKA was performed in three knees for periprosthetic joint infection (n = 2 knees) and tibial component loosening (n = 1 knee). The Kaplan–Meier 10- and 13-year prosthesis survival rates were 97.1% and 93.2%, respectively. The current study suggests that the mid-to long-term results of TKA in patients with hemophilic arthropathy are favorable, with successful long-term prosthesis survival achievable in most cases. MDPI 2020-10-11 /pmc/articles/PMC7601478/ /pubmed/33050640 http://dx.doi.org/10.3390/jcm9103247 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bae, Jung-Kwon
Kim, Kang-Il
Lee, Sang-Hak
Yoo, Myung-Chul
Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy
title Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy
title_full Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy
title_fullStr Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy
title_full_unstemmed Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy
title_short Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy
title_sort mid-to long-term survival of total knee arthroplasty in hemophilic arthropathy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601478/
https://www.ncbi.nlm.nih.gov/pubmed/33050640
http://dx.doi.org/10.3390/jcm9103247
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