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Application of CRISPR/Cas9-Based Reverse Genetics in Leishmania braziliensis: Conserved Roles for HSP100 and HSP23

The protozoan parasite Leishmania (Viannia) braziliensis (L. braziliensis) is the main cause of human tegumentary leishmaniasis in the New World, a disease affecting the skin and/or mucosal tissues. Despite its importance, the study of the unique biology of L. braziliensis through reverse genetics a...

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Detalles Bibliográficos
Autores principales: Adaui, Vanessa, Kröber-Boncardo, Constanze, Brinker, Christine, Zirpel, Henner, Sellau, Julie, Arévalo, Jorge, Dujardin, Jean-Claude, Clos, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601497/
https://www.ncbi.nlm.nih.gov/pubmed/33007987
http://dx.doi.org/10.3390/genes11101159

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