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G-CSF and G-CSFR Induce a Pro-Tumorigenic Macrophage Phenotype to Promote Colon and Pancreas Tumor Growth
SIMPLE SUMMARY: The gastrointestinal tumor microenvironment is regulated by cytokine production from the tumor and adjacent immune cells. G-CSFR is a cytokine that is highly produced in the gastrointestinal tumor microenvironment and may have unrecognized pro-tumorigenic activities. Here, we explore...
Autores principales: | Karagiannidis, Ioannis, de Santana Van Vilet, Eliane, Said Abu Egal, Erika, Phinney, Brandon, Jacenik, Damian, Prossnitz, Eric R., Beswick, Ellen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601499/ https://www.ncbi.nlm.nih.gov/pubmed/33036138 http://dx.doi.org/10.3390/cancers12102868 |
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