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G-CSF and G-CSFR Induce a Pro-Tumorigenic Macrophage Phenotype to Promote Colon and Pancreas Tumor Growth

SIMPLE SUMMARY: The gastrointestinal tumor microenvironment is regulated by cytokine production from the tumor and adjacent immune cells. G-CSFR is a cytokine that is highly produced in the gastrointestinal tumor microenvironment and may have unrecognized pro-tumorigenic activities. Here, we explore...

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Detalles Bibliográficos
Autores principales: Karagiannidis, Ioannis, de Santana Van Vilet, Eliane, Said Abu Egal, Erika, Phinney, Brandon, Jacenik, Damian, Prossnitz, Eric R., Beswick, Ellen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601499/
https://www.ncbi.nlm.nih.gov/pubmed/33036138
http://dx.doi.org/10.3390/cancers12102868

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