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Repeated Administration of Baclofen Modulates TRPV-1 Channel Expression by PKC Pathway in Dorsal Root Ganglia of Spinal Cord in a Morphine Tolerance Model of Rats

BACKGROUND: Tolerance and dependence to anti-nociceptive effect of morphine restricted its use. Nowadays co-administration of morphine and other drugs suggests diminishing this tolerance. Baclofen is one of the drugs that may be beneficial in the attenuation of tolerance to morphine. Studies have sh...

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Detalles Bibliográficos
Autores principales:	Mehrabadi, Shima, Karimiyan, Seyed Morteza, Ashabi, Ghorbangol, Moradbeygi, Khadijeh, Hoseini, Marjan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pasteur Institute of Iran 2020
Materias:	Full Length
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601548/ https://www.ncbi.nlm.nih.gov/pubmed/32660223 http://dx.doi.org/10.29252/ibj.24.6.374

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