Cargando…

CoQ(10) Deficient Endothelial Cell Culture Model for the Investigation of CoQ(10) Blood–Brain Barrier Transport

Primary coenzyme Q(10) (CoQ(10)) deficiency is unique among mitochondrial respiratory chain disorders in that it is potentially treatable if high-dose CoQ(10) supplements are given in the early stages of the disease. While supplements improve peripheral abnormalities, neurological symptoms are only...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wainwright, Luke, Hargreaves, Iain P., Georgian, Ana R., Turner, Charles, Dalton, R. Neil, Abbott, N. Joan, Heales, Simon J. R., Preston, Jane E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601674/ https://www.ncbi.nlm.nih.gov/pubmed/33050406 http://dx.doi.org/10.3390/jcm9103236

Ejemplares similares

CoQ10 and Aging
por: de Barcelos, Isabella Peixoto, et al.
Publicado: (2019)

The Important Role of CoQ(10) in Aging
por: López-Lluch, Guillermo
Publicado: (2019)

4‐Hydroxybenzoic acid restores CoQ(10) biosynthesis in human COQ2 deficiency
por: Herebian, Diran, et al.
Publicado: (2017)

Treatment of CoQ(10) Deficient Fibroblasts with Ubiquinone, CoQ Analogs, and Vitamin C: Time- and Compound-Dependent Effects
por: López, Luis C., et al.
Publicado: (2010)

Fluorene intercalated graphene oxide based CoQ10 imprinted polymer composite as a selective platform for electrochemical sensing of CoQ10
por: Soomro, Anam Naz, et al.
Publicado: (2022)

Effects of CoQ10 Replacement Therapy on the Audiological Characteristics of Pediatric Patients with COQ6 Variants
por: Nam, Dong Woo, et al.
Publicado: (2022)

Characterization of Arabidopsis thaliana Coq9 in the CoQ Biosynthetic Pathway
por: Hu, Mei, et al.
Publicado: (2023)

COQ4 Mutations Cause a Broad Spectrum of Mitochondrial Disorders Associated with CoQ(10) Deficiency
por: Brea-Calvo, Gloria, et al.
Publicado: (2015)

Novel recessive mutations in COQ4 cause severe infantile cardiomyopathy and encephalopathy associated with CoQ(10) deficiency
por: Sondheimer, Neal, et al.
Publicado: (2017)

Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy
por: Pu, Tian-Tian, et al.
Publicado: (2023)

Liposome/gold hybrid nanoparticle encoded with CoQ10 (LGNP-CoQ10) suppressed rheumatoid arthritis via STAT3/Th17 targeting
por: Jhun, Jooyeon, et al.
Publicado: (2020)

Manganese-driven CoQ deficiency
por: Diessl, Jutta, et al.
Publicado: (2022)

Lethal Neonatal CoQ Deficiency due to a COQ9 Variant
por: Finsterer, Josef, et al.
Publicado: (2018)

CoQ10-related sustained remission of proteinuria in a child with COQ6 glomerulopathy—a case report
por: Stańczyk, Małgorzata, et al.
Publicado: (2018)

Self-reported adherence and biomarker levels of CoQ10 and alpha-tocopherol
por: Vitolins, Mara Z, et al.
Publicado: (2018)

Identification of novel coenzyme Q(10) biosynthetic proteins Coq11 and Coq12 in Schizosaccharomyces pombe
por: Nishida, Ikuhisa, et al.
Publicado: (2023)

Effects of Inhibiting CoQ(10) Biosynthesis with 4-nitrobenzoate in Human Fibroblasts
por: Quinzii, Catarina M., et al.
Publicado: (2012)

Mitochondrial Disease and the Kidney With a Special Focus on CoQ(10) Deficiency
por: Schijvens, Anne M., et al.
Publicado: (2020)

Improving CoQ(10) productivity by strengthening glucose transmembrane of Rhodobacter sphaeroides
por: Yang, Yuying, et al.
Publicado: (2021)

CoQ(10) and Resveratrol Effects to Ameliorate Aged-Related Mitochondrial Dysfunctions
por: Gherardi, Gaia, et al.
Publicado: (2022)

Method for detecting CoQ10 incorporation in the mitochondrial respiratory chain supercomplex
por: Sugawara, Kyousuke, et al.
Publicado: (2023)

Coenzyme Q10 Phytosome Formulation Improves CoQ10 Bioavailability and Mitochondrial Functionality in Cultured Cells
por: Rizzardi, Nicola, et al.
Publicado: (2021)

Formation of Temporary Negative Ions and Their Subsequent Fragmentation upon Electron Attachment to CoQ(0) and CoQ(0)H(2)
por: Ameixa, João, et al.
Publicado: (2022)

Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-Synthome
por: He, Cuiwen H., et al.
Publicado: (2017)

CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity
por: Zhong, Xiali, et al.
Publicado: (2017)

Assessment of Serum CoQ10 Levels and other Antioxidant Markers in Breast Cancer
por: El-Attar, Eman, et al.
Publicado: (2020)

Elevated levels of mitochondrial CoQ(10) induce ROS-mediated apoptosis in pancreatic cancer
por: Dadali, Tulin, et al.
Publicado: (2021)

Ubiad1 Is an Antioxidant Enzyme that Regulates eNOS Activity by CoQ10 Synthesis
por: Mugoni, Vera, et al.
Publicado: (2013)

Therapeutic Effects of the Combination of Alpha-Lipoic Acid (ALA) and Coenzyme Q10 (CoQ10) on Cisplatin-Induced Nephrotoxicity
por: Khalifa, Eman Aly, et al.
Publicado: (2020)

CoQ(10)Phytosomes Improve Cellular Ubiquinone Uptake in Skeletal Muscle Cells: An Ex Vivo Study Using CoQ(10)-Enriched Low-Density Lipoproteins Obtained in a Randomized Crossover Study
por: Marcheggiani, Fabio, et al.
Publicado: (2023)

CoQ10-loaded liposomes combined with UTMD prevented early nephropathy of diabetic rats
por: Chen, Pian-Pian, et al.
Publicado: (2018)

Clinical Efficacy of Topical CoQ10 and Vitamin-E Eye-drop in Retinopathy of Prematurity
por: Akdogan, Muberra, et al.
Publicado: (2019)

Plasma CoQ10 Status in Patients with Propionic Acidaemia and Possible Benefit of Treatment with Ubiquinol
por: Stanescu, Sinziana, et al.
Publicado: (2022)

The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency
por: González-García, Pilar, et al.
Publicado: (2022)

Cellular Models for Primary CoQ Deficiency Pathogenesis Study
por: Santos-Ocaña, Carlos, et al.
Publicado: (2021)

Propargylation of CoQ0 through the Redox Chain Reaction
por: Pawlowski, Robert, et al.
Publicado: (2021)

Additive enhancement of wound healing in diabetic mice by low level light and topical CoQ10
por: Mao, Zhigang, et al.
Publicado: (2016)

CoQ10 in progressive supranuclear palsy: A randomized, placebo-controlled, double-blind trial
por: Apetauerova, Diana, et al.
Publicado: (2016)

CoQ(10) reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation
por: Frontiñán-Rubio, Javier, et al.
Publicado: (2022)

CoQ10 and Endothelial Function in Asians from Korea compared to Asians born in the United States and US Born Caucasians
por: Petrofsky, Jerrold Scott, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_dn38l3rpbcev0mcuognvo6a7hi