Human Serum Albumin Binds Native Insulin and Aggregable Insulin Fragments and Inhibits Their Aggregation

The purpose of this study was to investigate whether Human Serum Albumin (HSA) can bind native human insulin and its A13–A19 and B12–B17 fragments, which are responsible for the aggregation of the whole hormone. To label the hormone and both hot spots, so that their binding positions within the HSA...

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Detalles Bibliográficos
Autores principales: Wasko, Joanna, Wolszczak, Marian, Kaminski, Zbigniew J., Steblecka, Malgorzata, Kolesinska, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601681/
https://www.ncbi.nlm.nih.gov/pubmed/32992893
http://dx.doi.org/10.3390/biom10101366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601681/
https://www.ncbi.nlm.nih.gov/pubmed/32992893
http://dx.doi.org/10.3390/biom10101366

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