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Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults

The multicomponent training (MCT) effect on bone health in frail and pre-frail elders, which is influenced by dietary intake, is still unknown. The objective of this non-randomized intervention trial was to assess the effects of a 6-month MCT on bone structure in frail and pre-frail elders, and to a...

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Autores principales: Moradell, Ana, Navarrete-Villanueva, David, Fernández-García, Ángel I., Marín-Puyalto, Jorge, Gómez-Bruton, Alejandro, Pedrero-Chamizo, Raquel, Pérez-Gómez, Jorge, Ara, Ignacio, Casajus, Jose A., Gómez-Cabello, Alba, Vicente-Rodríguez, Germán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601843/
https://www.ncbi.nlm.nih.gov/pubmed/33019701
http://dx.doi.org/10.3390/nu12103016
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author Moradell, Ana
Navarrete-Villanueva, David
Fernández-García, Ángel I.
Marín-Puyalto, Jorge
Gómez-Bruton, Alejandro
Pedrero-Chamizo, Raquel
Pérez-Gómez, Jorge
Ara, Ignacio
Casajus, Jose A.
Gómez-Cabello, Alba
Vicente-Rodríguez, Germán
author_facet Moradell, Ana
Navarrete-Villanueva, David
Fernández-García, Ángel I.
Marín-Puyalto, Jorge
Gómez-Bruton, Alejandro
Pedrero-Chamizo, Raquel
Pérez-Gómez, Jorge
Ara, Ignacio
Casajus, Jose A.
Gómez-Cabello, Alba
Vicente-Rodríguez, Germán
author_sort Moradell, Ana
collection PubMed
description The multicomponent training (MCT) effect on bone health in frail and pre-frail elders, which is influenced by dietary intake, is still unknown. The objective of this non-randomized intervention trial was to assess the effects of a 6-month MCT on bone structure in frail and pre-frail elders, and to analyse the influence of dietary intake and serum vitamin D (25(OH)D) in these changes. Thirty MCT (TRAIN) and sixteen controls (CON), frail and pre-frail completed the information required for this study. Peripheral quantitative computed tomography measurements were taken at 4% and 38% of the tibia length and dietary intake was registered. The 25(OH)D values were obtained from blood samples. Analyses of covariance (ANCOVA) for repeated measures showed significant decreases for CON in total bone mineral content at 38% of tibia length. One factor ANOVAs showed smaller decreases in bone mineral density and cortical thickness percentage of change in TRAIN compared to CON. Linear regression analyses were performed to study the influence of nutrients and 25(OH)D on bone changes. Alcohol showed a negative influence on fracture index changes, while polyunsaturated fatty acid and vitamin A showed a positive association with some bone variables. The 25(OH)D only affected positively the cortical bone mineral density. In conclusion, our MCT seems to slow down some of the bone detriments associated with ageing in frail and pre-frail older adults, with alcohol showing a negative effect on the bone and apparent limited effect of nutrients and serum 25(OH)D on training related changes.
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spelling pubmed-76018432020-11-01 Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults Moradell, Ana Navarrete-Villanueva, David Fernández-García, Ángel I. Marín-Puyalto, Jorge Gómez-Bruton, Alejandro Pedrero-Chamizo, Raquel Pérez-Gómez, Jorge Ara, Ignacio Casajus, Jose A. Gómez-Cabello, Alba Vicente-Rodríguez, Germán Nutrients Article The multicomponent training (MCT) effect on bone health in frail and pre-frail elders, which is influenced by dietary intake, is still unknown. The objective of this non-randomized intervention trial was to assess the effects of a 6-month MCT on bone structure in frail and pre-frail elders, and to analyse the influence of dietary intake and serum vitamin D (25(OH)D) in these changes. Thirty MCT (TRAIN) and sixteen controls (CON), frail and pre-frail completed the information required for this study. Peripheral quantitative computed tomography measurements were taken at 4% and 38% of the tibia length and dietary intake was registered. The 25(OH)D values were obtained from blood samples. Analyses of covariance (ANCOVA) for repeated measures showed significant decreases for CON in total bone mineral content at 38% of tibia length. One factor ANOVAs showed smaller decreases in bone mineral density and cortical thickness percentage of change in TRAIN compared to CON. Linear regression analyses were performed to study the influence of nutrients and 25(OH)D on bone changes. Alcohol showed a negative influence on fracture index changes, while polyunsaturated fatty acid and vitamin A showed a positive association with some bone variables. The 25(OH)D only affected positively the cortical bone mineral density. In conclusion, our MCT seems to slow down some of the bone detriments associated with ageing in frail and pre-frail older adults, with alcohol showing a negative effect on the bone and apparent limited effect of nutrients and serum 25(OH)D on training related changes. MDPI 2020-10-01 /pmc/articles/PMC7601843/ /pubmed/33019701 http://dx.doi.org/10.3390/nu12103016 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Moradell, Ana
Navarrete-Villanueva, David
Fernández-García, Ángel I.
Marín-Puyalto, Jorge
Gómez-Bruton, Alejandro
Pedrero-Chamizo, Raquel
Pérez-Gómez, Jorge
Ara, Ignacio
Casajus, Jose A.
Gómez-Cabello, Alba
Vicente-Rodríguez, Germán
Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults
title Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults
title_full Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults
title_fullStr Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults
title_full_unstemmed Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults
title_short Role of Dietary Intake and Serum 25(OH)D on the Effects of a Multicomponent Exercise Program on Bone Mass and Structure of Frail and Pre-Frail Older Adults
title_sort role of dietary intake and serum 25(oh)d on the effects of a multicomponent exercise program on bone mass and structure of frail and pre-frail older adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601843/
https://www.ncbi.nlm.nih.gov/pubmed/33019701
http://dx.doi.org/10.3390/nu12103016
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