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Characterization of a PERK Kinase Inhibitor with Anti-Myeloma Activity

SIMPLE SUMMARY: Multiple myeloma is a bone marrow cancer that represents a severe health threat. The drugs used nowadays in chemotherapy often encounter resistance leading to a dramatic loss of their efficacy, which consequently affects patients’ survival. Previous studies have shown that the protei...

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Detalles Bibliográficos
Autores principales: Bagratuni, Tina, Patseas, Dimitrios, Mavrianou-Koutsoukou, Nefeli, Liacos, Christine Ivy, Sklirou, Aimilia D., Rousakis, Pantelis, Gavriatopoulou, Maria, Terpos, Evangelos, Tsitsilonis, Ourania E., Trougakos, Ioannis P., Kastritis, Efstathios, Dimopoulos, Meletios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601861/
https://www.ncbi.nlm.nih.gov/pubmed/33028016
http://dx.doi.org/10.3390/cancers12102864