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Cognitive Impairment in the 3xTg-AD Mouse Model of Alzheimer’s Disease is Affected by Aβ-ImmunoTherapy and Cognitive Stimulation

Clinical symptoms of Alzheimer’s Disease (AD) include behavioral alterations and cognitive impairment. These functional phenotypes early occur in triple-transgenic (3xTg-AD) mice. Specifically, behavioral alterations are first detected when mice are at around 2.5 months old and cognitive impairment...

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Detalles Bibliográficos
Autores principales: Roda, Alejandro R., Esquerda-Canals, Gisela, Martí-Clúa, Joaquim, Villegas, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601886/
https://www.ncbi.nlm.nih.gov/pubmed/33023109
http://dx.doi.org/10.3390/pharmaceutics12100944