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Cognitive Impairment in the 3xTg-AD Mouse Model of Alzheimer’s Disease is Affected by Aβ-ImmunoTherapy and Cognitive Stimulation
Clinical symptoms of Alzheimer’s Disease (AD) include behavioral alterations and cognitive impairment. These functional phenotypes early occur in triple-transgenic (3xTg-AD) mice. Specifically, behavioral alterations are first detected when mice are at around 2.5 months old and cognitive impairment...
Autores principales: | Roda, Alejandro R., Esquerda-Canals, Gisela, Martí-Clúa, Joaquim, Villegas, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601886/ https://www.ncbi.nlm.nih.gov/pubmed/33023109 http://dx.doi.org/10.3390/pharmaceutics12100944 |
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