Cargando…

Acute Effects of Metformin and Vildagliptin after a Lipid-Rich Meal on Postprandial Microvascular Reactivity in Patients with Type 2 Diabetes and Obesity: A Randomized Trial

Background: Type 2 diabetes mellitus and obesity are both related to endothelial dysfunction. Postprandial lipemia is a cardiovascular risk. Notably, it is known that a high-fat diet may elicit microvascular dysfunction, even in healthy subjects. Since anti-diabetic drugs have different mechanisms o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schiappacassa, Alessandra, Maranhão, Priscila A., de Souza, Maria das Graças Coelho, Panazzolo, Diogo G., Nogueira Neto, José Firmino, Bouskela, Eliete, Kraemer-Aguiar, Luiz Guilherme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601890/ https://www.ncbi.nlm.nih.gov/pubmed/33050169 http://dx.doi.org/10.3390/jcm9103228

Ejemplares similares

Metabolic Changes Induced by High-Fat Meal Evoke Different Microvascular Responses in Accordance with Adiposity Status
por: Maranhão, Priscila Alves, et al.
Publicado: (2018)

30-days effects of vildagliptin on vascular function, plasma viscosity, inflammation, oxidative stress, and intestinal peptides on drug-naïve women with diabetes and obesity: a randomized head-to-head metformin-controlled study
por: Schiapaccassa, Alessandra, et al.
Publicado: (2019)

Effects of a high-fat meal on inflammatory and endothelial injury biomarkers in accordance with adiposity status: a cross-sectional study
por: de Souza, Maria das Graças Coelho, et al.
Publicado: (2022)

Obesity, metabolic syndrome, impaired fasting glucose, and microvascular dysfunction: a principal component analysis approach
por: Panazzolo, Diogo G, et al.
Publicado: (2012)

Microvascular Function, Inflammatory Status, and Oxidative Stress in Post-Bariatric Patients with Weight Regain
por: Lopes, Karynne Grutter, et al.
Publicado: (2023)

Dipeptidyl Peptidase 4 Activity Is Related to Body Composition, Measures of Adiposity, and Insulin Resistance in Subjects with Excessive Adiposity and Different Degrees of Glucose Tolerance
por: Silva Júnior, Wellington S., et al.
Publicado: (2019)

Structural and functional changes in the microcirculation of lepromatous leprosy patients - Observation using orthogonal polarization spectral imaging and laser Doppler flowmetry iontophoresis
por: Treu, Curt, et al.
Publicado: (2017)

Tuberculoid leprosy: An in vivo microvascular evaluation of cutaneous lesions
por: Pino, Livia, et al.
Publicado: (2020)

Gender differences in microcirculation: Observation using the hamster cheek pouch
por: Panazzolo, Diogo Guarnieri, et al.
Publicado: (2013)

Brazil nuts intake improves lipid profile, oxidative stress and microvascular function in obese adolescents: a randomized controlled trial
por: Maranhão, Priscila A, et al.
Publicado: (2011)

Short-Term Treatment with Metformin Improves the Cardiovascular Risk Profile in First-Degree Relatives of Subjects with Type 2 Diabetes Mellitus who have a Metabolic Syndrome and Normal Glucose Tolerance without Changes in C-Reactive Protein or Fibrinogen
por: de Lima, Luis Mauro Alvim, et al.
Publicado: (2009)

n-3 PUFA Induce Microvascular Protective Changes During Ischemia/Reperfusion
por: Souza, Maria das Graças Coelho de, et al.
Publicado: (2014)

Ghrelin and glucagon-like peptide-1 according to body adiposity and glucose homeostasis
por: Lopes, Karynne Grutter, et al.
Publicado: (2023)

Data on vildagliptin and vildagliptin plus metformin combination in type-2 diabetes mellitus management
por: Das, Sambit, et al.
Publicado: (2021)

Effects of physical training on physical and functional fitness, physical activity level, endothelial function, hemodynamic variables, bone metabolism, and quality of life of post-bariatric patients: study protocol for a randomized controlled trial
por: Lopes, Karynne Grutter, et al.
Publicado: (2022)

Vildagliptin/metformin: Lactic acidosis and hypoglycaemia: case report
Publicado: (2022)

Single administration of vildagliptin attenuates postprandial hypertriglyceridemia and endothelial dysfunction in normoglycemic individuals
por: NOGUCHI, KAORU, et al.
Publicado: (2015)

Comparison of Vildagliptin-Metformin and Glimepiride-Metformin Treatments in Type 2 Diabetic Patients
por: Jeon, Hyun Jeong, et al.
Publicado: (2011)

Microcirculation, Adiposity, and Traditional and Emerging Cardiovascular Risk Factors in Prepubertal Children
por: Bastos da Cunha, Carolina, et al.
Publicado: (2017)

Chronic Aerobic Exercise Associated to Dietary Modification Improve Endothelial Function and eNOS Expression in High Fat Fed Hamsters
por: Boa, Beatriz C. S., et al.
Publicado: (2014)

Endothelial Function and Insulin Resistance in Early Postmenopausal Women with Cardiovascular Risk Factors: Importance of ESR1 and NOS3 Polymorphisms
por: Clapauch, Ruth, et al.
Publicado: (2014)

Use of metformin and vildagliptin for treatment of type 2 diabetes in the elderly
por: Sicras-Mainar, Antoni, et al.
Publicado: (2014)

Hypoparathyroidism after Roux-en-Y gastric bypass - a challenge for clinical management: a case report
por: Panazzolo, Diogo Guarnieri, et al.
Publicado: (2014)

Effects of moderate and high intensity isocaloric aerobic training upon microvascular reactivity and myocardial oxidative stress in rats
por: Paes, Lorena, et al.
Publicado: (2020)

Strength training with blood flow restriction – a novel therapeutic approach for older adults with sarcopenia? A case report
por: Lopes, Karynne Grutter, et al.
Publicado: (2019)

Bioequivalence Studies of New Generic Formulations of Vildagliptin and Fixed-Drug Combination of Vildagliptin and Metformin Versus Respective Originator Products in Healthy Volunteers
por: Schnaars, Yvonne, et al.
Publicado: (2022)

Milrinone Attenuates Arteriolar Vasoconstriction and Capillary Perfusion Deficits on Endotoxemic Hamsters
por: de Miranda, Marcos Lopes, et al.
Publicado: (2015)

Effectiveness and Tolerability of Vildagliptin and the Single Pill Combination of Vildagliptin and Metformin in “Real-World” Management of Type 2 Diabetes Mellitus: The G-FORCE Study
por: Van Gaal, Luc, et al.
Publicado: (2019)

A 16-week study to compare the effect of vildagliptin versus gliclazide on postprandial lipoprotein concentrations and oxidative stress in patients with type 2 diabetes inadequately controlled with metformin monotherapy
por: Hissa, Marcelo R. Nasser, et al.
Publicado: (2015)

Vildagliptin efficacy in combination with metformin among Jordanian patients with type 2 diabetes mellitus inadequately controlled with metformin
por: Al Omari, Mousa, et al.
Publicado: (2016)

Comparison of Safety and Efficacy of Glimepiride-Metformin and Vildagliptin- Metformin Treatment in Newly Diagnosed Type 2 Diabetic Patients
por: Kumar, Surendra
Publicado: (2021)

High fat meals increases postprandial fat oxidation rate but not postprandial lipemia
por: Chiu, Chih-Hui, et al.
Publicado: (2019)

Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus
por: Ved, Paresh, et al.
Publicado: (2012)

Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus
por: Ved, Paresh, et al.
Publicado: (2013)

Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over three months in patients with type 2 diabetes mellitus’
por: Mundra, Vishal
Publicado: (2012)

Metabolic and Inflammatory Profiles of Post-Bariatric Patients with Weight Recidivism
por: Lopes, Karynne Grutter, et al.
Publicado: (2022)

Efficacy and Safety of Vildagliptin as Add-on to Metformin in Japanese Patients with Type 2 Diabetes Mellitus
por: Odawara, Masato, et al.
Publicado: (2014)

Comparison of Vildagliptin and Pioglitazone in Korean Patients with Type 2 Diabetes Inadequately Controlled with Metformin
por: Kim, Jong Ho, et al.
Publicado: (2016)

Real-World Observational Study on Vildagliptin With Insulin (VIL-INS) or Vildagliptin and Metformin With Insulin (VIL-MET-INS) Therapy in Indian Patients With Type 2 Diabetes Mellitus
por: Panneerselvam, P, et al.
Publicado: (2023)

Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet
por: Halimi, Serge, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_atb338o48mbkh9ot44jrqoo96p