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The Effects of Divalent Cation-Chelated Prion Fibrils on the Immune Response of EOC 13.31 Microglia Cells
Transmissible spongiform encephalopathies (TSEs) are epidemic neurodegenerative diseases caused by prion proteins; in particular, they are induced by misfolded prion proteins (PrP(Sc)). PrP(Sc) tend to aggregate into insoluble amyloid prion fibrils (fPrP(WT)), resulting in apoptosis of neuron cells...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602007/ https://www.ncbi.nlm.nih.gov/pubmed/33066249 http://dx.doi.org/10.3390/cells9102285 |