Cargando…

Srebf2 Locus Overexpression Reduces Body Weight, Total Cholesterol and Glucose Levels in Mice Fed with Two Different Diets

Macronutrients represent risk factors for hyperlipidemia or diabetes. Lipid alterations and type 2 diabetes mellitus are global health problems. Overexpression of sterol regulatory element-binding factor (Srebf2) in transgenic animals is linked to elevated cholesterol levels and diabetes development...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andrés-Blasco, Irene, Blesa, Sebastian, Vinué, Ángela, González-Navarro, Herminia, Real, José Tomás, Martínez-Hervás, Sergio, Carretero, Julián, Ferrández-Izquierdo, Antonio, Chaves, Felipe Javier, García-García, Ana-Bárbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602228/ https://www.ncbi.nlm.nih.gov/pubmed/33066385 http://dx.doi.org/10.3390/nu12103130

Ejemplares similares

A Very Rare Variant in SREBF2, a Possible Cause of Hypercholesterolemia and Increased Glycemic Levels
por: García-García, Ana-Bárbara, et al.
Publicado: (2022)

Impact of Cholesterol Metabolism in Immune Cell Function and Atherosclerosis
por: Aguilar-Ballester, María, et al.
Publicado: (2020)

Understanding the Impact of Dietary Cholesterol on Chronic Metabolic Diseases through Studies in Rodent Models
por: Vinué, Ángela, et al.
Publicado: (2018)

Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes
por: Martínez-Hervás, Sergio, et al.
Publicado: (2019)

Tissue-specific changes in Srebf1 and Srebf2 expression and DNA methylation with perinatal phthalate exposure
por: Moody, Laura, et al.
Publicado: (2019)

Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance
por: Taberner-Cortés, Alida, et al.
Publicado: (2020)

SREBF1c and SREBF2 gene polymorphisms are associated with acute coronary syndrome and blood lipid levels in Mexican population
por: Vargas-Alarcon, Gilberto, et al.
Publicado: (2019)

Regulatory Roles of SREBF1 and SREBF2 in Lipid Metabolism and Deposition in Two Chinese Representative Fat-Tailed Sheep Breeds
por: Liang, Chen, et al.
Publicado: (2020)

SREBF2–STARD4 axis confers sorafenib resistance in hepatocellular carcinoma by regulating mitochondrial cholesterol homeostasis
por: Yue, Xuetian, et al.
Publicado: (2022)

Vitamin B(12) insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes
por: Adaikalakoteswari, Antonysunil, et al.
Publicado: (2015)

SREBF1 links lipogenesis to mitophagy and sporadic Parkinson disease
por: Ivatt, Rachael M, et al.
Publicado: (2014)

Srebf1a is a key regulator of transcriptional control for adipogenesis
por: Ayala-Sumuano, Jorge-Tonatiuh, et al.
Publicado: (2011)

Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death
por: Fan, Yue-Mei, et al.
Publicado: (2008)

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
por: Medina-Gomez, Carolina, et al.
Publicado: (2017)

CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF1
por: Lim, Jae Min, et al.
Publicado: (2023)

TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination
por: Ho, Wan Yun, et al.
Publicado: (2021)

Expression of miR-33 from an SREBF2 Intron Targets the FTO Gene in the Chicken
por: Shao, Fang, et al.
Publicado: (2014)

SREBF1 gene variations modulate insulin sensitivity in response to a fish oil supplementation
por: Bouchard-Mercier, Annie, et al.
Publicado: (2014)

Statin Treatment Induced a Lipogenic Expression Hierarchical Network Centered by SREBF2 in the Liver
por: Song, Shiyu, et al.
Publicado: (2021)

Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and SREBF1 Gene
por: Gründing, Anna Ricarda, et al.
Publicado: (2022)

TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability
por: Chen, Xintian, et al.
Publicado: (2023)

Dissecting Abdominal Aortic Aneurysm Is Aggravated by Genetic Inactivation of LIGHT (TNFSF14)
por: Herrero-Cervera, Andrea, et al.
Publicado: (2021)

Single Nucleotide Polymorphism of SREBF-1 Gene Associated with an Increased Risk of Endometrial Cancer in Chinese Women
por: Qiu, Chun-Ping, et al.
Publicado: (2014)

Srebf1c preserves hematopoietic stem cell function and survival as a switch of mitochondrial metabolism
por: Lu, Yukai, et al.
Publicado: (2022)

ARMC5-CUL3 E3 ligase targets full-length SREBF in adrenocortical tumors
por: Okuno, Yosuke, et al.
Publicado: (2022)

Different Impacts of Cardiovascular Risk Factors on Oxidative Stress
por: Mansego, Maria L., et al.
Publicado: (2011)

Smart Management Consumption in Renewable Energy Fed Ecosystems †
por: Ferrández-Pastor, Francisco Javier, et al.
Publicado: (2019)

Associations of the SREBF2 Gene and INSIG2 Polymorphisms with Obesity and Dyslipidemia in Thai Psychotic Disorder Patients Treated with Risperidone
por: Vanwong, Natchaya, et al.
Publicado: (2021)

Metabolic and Immunological Shifts during Mid-to-Late Gestation Influence Maternal Blood Methylation of CPT1A and SREBF1
por: Pavethynath, Shilpa, et al.
Publicado: (2019)

Circadian Gene PER2 Silencing Downregulates PPARG and SREBF1 and Suppresses Lipid Synthesis in Bovine Mammary Epithelial Cells
por: Jing, Yujia, et al.
Publicado: (2021)

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer
por: Li, Li-Yan, et al.
Publicado: (2021)

ApoM regulates PFKL through the transcription factor SREBF1 to inhibit the proliferation, migration and metastasis of liver cancer cells
por: Zhang, Xiao, et al.
Publicado: (2022)

mRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival
por: García-García, Ana-Barbara, et al.
Publicado: (2017)

Procyanidins in Theobroma cacao Reduce Plasma Cholesterol Levels in High Cholesterol-Fed Rats
por: Osakabe, Naomi, et al.
Publicado: (2009)

Urotensin II Promotes Atherosclerosis in Cholesterol-Fed Rabbits
por: Li, Yafeng, et al.
Publicado: (2014)

Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits
por: Niimi, Manabu, et al.
Publicado: (2013)

Unsaturated Oral Fat Load Test Improves Glycemia, Insulinemia and Oxidative Stress Status in Nondiabetic Subjects with Abdominal Obesity
por: Martinez-Hervas, Sergio, et al.
Publicado: (2016)

Ezetimibe and Simvastatin Reduce Cholesterol Levels in Zebrafish Larvae Fed a High-Cholesterol Diet
por: Baek, Ji Sun, et al.
Publicado: (2012)

Polymorphisms in Endothelin System Genes, Arsenic Levels and Obesity Risk
por: Martínez-Barquero, Vanesa, et al.
Publicado: (2015)

Inhibition of expression of P-selectin by antioxidant in cholesterol-fed rats.
por: Lee, C. S., et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_podrpqfr1nusfqe6joiectsq11