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Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies
Two new copper complexes of hyperbranched polymers modified with dansyl units were synthesized and characterized by infrared spectroscopy (IR) and electron paramagnetic resonance (EPR) techniques. It was found that copper ions coordinate predominantly with nitrogen or oxygen atoms of the polymer mol...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602284/ https://www.ncbi.nlm.nih.gov/pubmed/33066584 http://dx.doi.org/10.3390/ma13204574 |
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author | Bosch, Paula Staneva, Desislava Vasileva-Tonkova, Evgenia Grozdanov, Petar Nikolova, Ivanka Kukeva, Rositsa Stoyanova, Radostina Grabchev, Ivo |
author_facet | Bosch, Paula Staneva, Desislava Vasileva-Tonkova, Evgenia Grozdanov, Petar Nikolova, Ivanka Kukeva, Rositsa Stoyanova, Radostina Grabchev, Ivo |
author_sort | Bosch, Paula |
collection | PubMed |
description | Two new copper complexes of hyperbranched polymers modified with dansyl units were synthesized and characterized by infrared spectroscopy (IR) and electron paramagnetic resonance (EPR) techniques. It was found that copper ions coordinate predominantly with nitrogen or oxygen atoms of the polymer molecule. The place of the formation of complexes and the number of copper ions involved depend on the chemical structure of the polymer. The antimicrobial activity of the new polymers and their Cu(II) complexes was tested against Gram-negative and Gram-positive bacterial and fungal strains. Copper complexes were found to have activity better than that of the corresponding ligands. The deposition of the modified branched polymers onto cotton fabrics prevents the formation of bacterial biofilms, which indicates that the studied polymers can find application in antibacterial textiles. |
format | Online Article Text |
id | pubmed-7602284 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76022842020-11-01 Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies Bosch, Paula Staneva, Desislava Vasileva-Tonkova, Evgenia Grozdanov, Petar Nikolova, Ivanka Kukeva, Rositsa Stoyanova, Radostina Grabchev, Ivo Materials (Basel) Article Two new copper complexes of hyperbranched polymers modified with dansyl units were synthesized and characterized by infrared spectroscopy (IR) and electron paramagnetic resonance (EPR) techniques. It was found that copper ions coordinate predominantly with nitrogen or oxygen atoms of the polymer molecule. The place of the formation of complexes and the number of copper ions involved depend on the chemical structure of the polymer. The antimicrobial activity of the new polymers and their Cu(II) complexes was tested against Gram-negative and Gram-positive bacterial and fungal strains. Copper complexes were found to have activity better than that of the corresponding ligands. The deposition of the modified branched polymers onto cotton fabrics prevents the formation of bacterial biofilms, which indicates that the studied polymers can find application in antibacterial textiles. MDPI 2020-10-14 /pmc/articles/PMC7602284/ /pubmed/33066584 http://dx.doi.org/10.3390/ma13204574 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bosch, Paula Staneva, Desislava Vasileva-Tonkova, Evgenia Grozdanov, Petar Nikolova, Ivanka Kukeva, Rositsa Stoyanova, Radostina Grabchev, Ivo Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies |
title | Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies |
title_full | Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies |
title_fullStr | Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies |
title_full_unstemmed | Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies |
title_short | Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies |
title_sort | hyperbranched polymers modified with dansyl units and their cu(ii) complexes. bioactivity studies |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602284/ https://www.ncbi.nlm.nih.gov/pubmed/33066584 http://dx.doi.org/10.3390/ma13204574 |
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