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Overcoming the Solubility Barrier of Ibuprofen by the Rational Process Design of a Nanocrystal Formulation

Wet media milling, coupled with spay drying, is a commonly proposed formulation strategy for the production and solidification of nanosuspensions in order to overcome the solubility barrier of BCS Class II substances. However, the application of mechanically and thermally intensive processes is not...

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Detalles Bibliográficos
Autores principales:	Ouranidis, Andreas, Gkampelis, Nikos, Vardaka, Elisavet, Karagianni, Anna, Tsiptsios, Dimitrios, Nikolakakis, Ioannis, Kachrimanis, Kyriakos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602516/ https://www.ncbi.nlm.nih.gov/pubmed/33066680 http://dx.doi.org/10.3390/pharmaceutics12100969

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