Brain-Targeted Delivery of Pre-miR-29b Using Lactoferrin-Stearic Acid-Modified-Chitosan/Polyethyleneimine Polyplexes

The efficacy of brain therapeutics is largely hampered by the presence of the blood–brain barrier (BBB), mainly due to the failure of most (bio) pharmaceuticals to cross it. Accordingly, this study aims to develop nanocarriers for targeted delivery of recombinant precursor microRNA (pre-miR-29b), fo...

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Detalles Bibliográficos
Autores principales: Pereira, Patrícia, Barreira, Maria, Cruz, Carla, Tomás, Joana, Luís, Ângelo, Pedro, Augusto Q., Queiroz, João A., Sousa, Fani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602608/
https://www.ncbi.nlm.nih.gov/pubmed/33076502
http://dx.doi.org/10.3390/ph13100314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602608/
https://www.ncbi.nlm.nih.gov/pubmed/33076502
http://dx.doi.org/10.3390/ph13100314

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