Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline

IMPORTANCE: Adults with Down syndrome (DS) are at high‐risk of revealing Alzheimer's disease (AD) pathology, in part due to the triplication of chromosome 21 encoding the amyloid precursor protein. Adults with DS are uniformly affected by AD pathology by their 30′s and have a 70% to 80% chance...

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Detalles Bibliográficos
Autores principales: Tudorascu, DL, Laymon, CM, Zammit, M, Minhas, DS, Anderson, SJ, Ellison, PA, Zaman, S, Ances, BM, Sabbagh, M, Johnson, SC, Mathis, CA, Klunk, WE, Handen, BL, Christian, BT, Cohen, AD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602678/
https://www.ncbi.nlm.nih.gov/pubmed/33163613
http://dx.doi.org/10.1002/trc2.12096

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