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Metabolic Effects of Selective Deletion of Group VIA Phospholipase A(2) from Macrophages or Pancreatic Islet Beta-Cells

To examine the role of group VIA phospholipase A(2) (iPLA(2)β) in specific cell lineages in insulin secretion and insulin action, we prepared mice with a selective iPLA(2)β deficiency in cells of myelomonocytic lineage, including macrophages (MØ-iPLA(2)β-KO), or in insulin-secreting β-cells (β-Cell-...

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Detalles Bibliográficos
Autores principales: Turk, John, Song, Haowei, Wohltmann, Mary, Frankfater, Cheryl, Lei, Xiaoyong, Ramanadham, Sasanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602969/
https://www.ncbi.nlm.nih.gov/pubmed/33080873
http://dx.doi.org/10.3390/biom10101455