Cargando…
Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study
(1) Background: Balance decline is highly prevalent in people suffering from chronic ankle instability (CAI). The control of balance depends upon multiple neurophysiologic systems including the activation of cortical brain regions (e.g., the primary sensorimotor cortex). The excitability of this reg...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602979/ https://www.ncbi.nlm.nih.gov/pubmed/33080863 http://dx.doi.org/10.3390/brainsci10100749 |
_version_ | 1783603813282742272 |
---|---|
author | Ma, Yuanbo Yin, Keyi Zhuang, Wei Zhang, Cui Jiang, Yong Huang, Jin Manor, Brad Zhou, Junhong Liu, Yu |
author_facet | Ma, Yuanbo Yin, Keyi Zhuang, Wei Zhang, Cui Jiang, Yong Huang, Jin Manor, Brad Zhou, Junhong Liu, Yu |
author_sort | Ma, Yuanbo |
collection | PubMed |
description | (1) Background: Balance decline is highly prevalent in people suffering from chronic ankle instability (CAI). The control of balance depends upon multiple neurophysiologic systems including the activation of cortical brain regions (e.g., the primary sensorimotor cortex). The excitability of this region, however, is diminished in people with CAI. In this pilot double-blinded randomized controlled trial, we tested the effects of high-definition transcranial direct current stimulation (HD-tDCS) designed to facilitate the excitability of M1 and S1 in combination with short-foot exercise (SFE) training on proprioception and dynamic balance performance in individuals with CAI. (2) Methods: Thirty young adults completed baseline assessments including the Active Movement Extent Discrimination Apparatus (AMEDA), Joint Position Reproduction (JPR) test, Y-balance test, and the Sensory Organization Test (SOT). They were then randomized to receive a four-week intervention of SFE in combination with tDCS (i.e., HD-tDCS+SFE) or sham (i.e., control) stimulation. Baseline assessments were repeated once-weekly throughout the intervention and during a two-week follow-up period. (3) Results: Twenty-eight participants completed this study. Blinding procedures were successful and no adverse events were reported. As compared to the control group, the HD-tDCS+SFE group exhibited significant improvements in the JPR test, the Y balance test, and the SOT at different time points. No group by time interaction was observed in AMEDA test performance. (4) Conclusions: HD-tDCS combined with SFE may improve dynamic balance and proprioception in CAI. Larger, more definitive trials with extended follow-up are warranted. |
format | Online Article Text |
id | pubmed-7602979 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76029792020-11-01 Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study Ma, Yuanbo Yin, Keyi Zhuang, Wei Zhang, Cui Jiang, Yong Huang, Jin Manor, Brad Zhou, Junhong Liu, Yu Brain Sci Article (1) Background: Balance decline is highly prevalent in people suffering from chronic ankle instability (CAI). The control of balance depends upon multiple neurophysiologic systems including the activation of cortical brain regions (e.g., the primary sensorimotor cortex). The excitability of this region, however, is diminished in people with CAI. In this pilot double-blinded randomized controlled trial, we tested the effects of high-definition transcranial direct current stimulation (HD-tDCS) designed to facilitate the excitability of M1 and S1 in combination with short-foot exercise (SFE) training on proprioception and dynamic balance performance in individuals with CAI. (2) Methods: Thirty young adults completed baseline assessments including the Active Movement Extent Discrimination Apparatus (AMEDA), Joint Position Reproduction (JPR) test, Y-balance test, and the Sensory Organization Test (SOT). They were then randomized to receive a four-week intervention of SFE in combination with tDCS (i.e., HD-tDCS+SFE) or sham (i.e., control) stimulation. Baseline assessments were repeated once-weekly throughout the intervention and during a two-week follow-up period. (3) Results: Twenty-eight participants completed this study. Blinding procedures were successful and no adverse events were reported. As compared to the control group, the HD-tDCS+SFE group exhibited significant improvements in the JPR test, the Y balance test, and the SOT at different time points. No group by time interaction was observed in AMEDA test performance. (4) Conclusions: HD-tDCS combined with SFE may improve dynamic balance and proprioception in CAI. Larger, more definitive trials with extended follow-up are warranted. MDPI 2020-10-17 /pmc/articles/PMC7602979/ /pubmed/33080863 http://dx.doi.org/10.3390/brainsci10100749 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ma, Yuanbo Yin, Keyi Zhuang, Wei Zhang, Cui Jiang, Yong Huang, Jin Manor, Brad Zhou, Junhong Liu, Yu Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study |
title | Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study |
title_full | Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study |
title_fullStr | Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study |
title_full_unstemmed | Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study |
title_short | Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study |
title_sort | effects of combining high-definition transcranial direct current stimulation with short-foot exercise on chronic ankle instability: a pilot randomized and double-blinded study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602979/ https://www.ncbi.nlm.nih.gov/pubmed/33080863 http://dx.doi.org/10.3390/brainsci10100749 |
work_keys_str_mv | AT mayuanbo effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT yinkeyi effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT zhuangwei effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT zhangcui effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT jiangyong effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT huangjin effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT manorbrad effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT zhoujunhong effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy AT liuyu effectsofcombininghighdefinitiontranscranialdirectcurrentstimulationwithshortfootexerciseonchronicankleinstabilityapilotrandomizedanddoubleblindedstudy |