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Dissecting the Crosstalk between NRF2 Signaling and Metabolic Processes in Cancer

SIMPLE SUMMARY: The stress-responsive transcription factor NRF2 (nuclear factor-erythroid 2 p45-related factor 2) directs cellular metabolic processes that can have diverse effects in the context of cancer. This review addresses how NRF2 and its negative regulator KEAP1 (Kelch-like ECH-associated pr...

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Detalles Bibliográficos
Autores principales: DeBlasi, Janine M., DeNicola, Gina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603127/
https://www.ncbi.nlm.nih.gov/pubmed/33080927
http://dx.doi.org/10.3390/cancers12103023