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Crosstalk of Hedgehog and mTORC1 Pathways

Hedgehog (Hh) signaling and mTOR signaling, essential for embryonic development and cellular metabolism, are both coordinated by the primary cilium. Observations from cancer cells strongly indicate crosstalk between Hh and mTOR signaling. This hypothesis is supported by several studies: Evidence poi...

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Detalles Bibliográficos
Autores principales: Larsen, Lasse Jonsgaard, Møller, Lisbeth Birk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603200/
https://www.ncbi.nlm.nih.gov/pubmed/33081032
http://dx.doi.org/10.3390/cells9102316

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