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Onychomycosis in Northwestern Greece over a 7-Year Period

Onychomycosis is considered as one of the major public health problems with a global distribution associated with geographic, demographic and environmental factors, underlying comorbidities and immunodeficiency disorders. This study was conducted to investigate the etiological agents of onychomycosi...

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Autores principales: Sakkas, Hercules, Kittas, Christos, Kapnisi, Georgia, Priavali, Efthalia, Kallinteri, Amalia, Bassukas, Ioannis D., Gartzonika, Konstantina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603248/
https://www.ncbi.nlm.nih.gov/pubmed/33080905
http://dx.doi.org/10.3390/pathogens9100851
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author Sakkas, Hercules
Kittas, Christos
Kapnisi, Georgia
Priavali, Efthalia
Kallinteri, Amalia
Bassukas, Ioannis D.
Gartzonika, Konstantina
author_facet Sakkas, Hercules
Kittas, Christos
Kapnisi, Georgia
Priavali, Efthalia
Kallinteri, Amalia
Bassukas, Ioannis D.
Gartzonika, Konstantina
author_sort Sakkas, Hercules
collection PubMed
description Onychomycosis is considered as one of the major public health problems with a global distribution associated with geographic, demographic and environmental factors, underlying comorbidities and immunodeficiency disorders. This study was conducted to investigate the etiological agents of onychomycosis, in Northwestern Greece during a 7-year period. The study population included 1095 outpatients with clinically suspected onychomycosis that presented to the University Hospital of Ioannina, NW Greece (2011–2017). Samples were examined for causative fungi, and mycological identification was established using standard mycological methods. Demographic data of each patient, comorbidities, localization of infection and history of previous fungal infection were collected. Onychomycosis was diagnosed in 317 of the 1095 suspected cases (28.9%) and the most frequently isolated pathogens were yeasts (50.8%) followed by dermatophytes (36.9%) and non-dermatophyte molds (NDMs) (12.3%). Dermatophytes were mostly involved in toenail onychomycosis (90.6%) and more commonly affected males than females (57.3% vs. 42.7%), while the predominantly isolated pathogen was Τrichophyton rubrum (74.4%) followed by Τrichophyton interdigitale (21.4%). Candida albicans was the most prevalent isolated yeast (82%), whereas among the cases with onychomycosis due to NDMs, Aspergillus spp. were isolated as the principal species (59%). Continuous monitoring should be performed in order to identify possible trends and shifts in species isolation rates and to evaluate the impact of onychomycosis among the general population and high-risk groups.
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spelling pubmed-76032482020-11-01 Onychomycosis in Northwestern Greece over a 7-Year Period Sakkas, Hercules Kittas, Christos Kapnisi, Georgia Priavali, Efthalia Kallinteri, Amalia Bassukas, Ioannis D. Gartzonika, Konstantina Pathogens Article Onychomycosis is considered as one of the major public health problems with a global distribution associated with geographic, demographic and environmental factors, underlying comorbidities and immunodeficiency disorders. This study was conducted to investigate the etiological agents of onychomycosis, in Northwestern Greece during a 7-year period. The study population included 1095 outpatients with clinically suspected onychomycosis that presented to the University Hospital of Ioannina, NW Greece (2011–2017). Samples were examined for causative fungi, and mycological identification was established using standard mycological methods. Demographic data of each patient, comorbidities, localization of infection and history of previous fungal infection were collected. Onychomycosis was diagnosed in 317 of the 1095 suspected cases (28.9%) and the most frequently isolated pathogens were yeasts (50.8%) followed by dermatophytes (36.9%) and non-dermatophyte molds (NDMs) (12.3%). Dermatophytes were mostly involved in toenail onychomycosis (90.6%) and more commonly affected males than females (57.3% vs. 42.7%), while the predominantly isolated pathogen was Τrichophyton rubrum (74.4%) followed by Τrichophyton interdigitale (21.4%). Candida albicans was the most prevalent isolated yeast (82%), whereas among the cases with onychomycosis due to NDMs, Aspergillus spp. were isolated as the principal species (59%). Continuous monitoring should be performed in order to identify possible trends and shifts in species isolation rates and to evaluate the impact of onychomycosis among the general population and high-risk groups. MDPI 2020-10-17 /pmc/articles/PMC7603248/ /pubmed/33080905 http://dx.doi.org/10.3390/pathogens9100851 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sakkas, Hercules
Kittas, Christos
Kapnisi, Georgia
Priavali, Efthalia
Kallinteri, Amalia
Bassukas, Ioannis D.
Gartzonika, Konstantina
Onychomycosis in Northwestern Greece over a 7-Year Period
title Onychomycosis in Northwestern Greece over a 7-Year Period
title_full Onychomycosis in Northwestern Greece over a 7-Year Period
title_fullStr Onychomycosis in Northwestern Greece over a 7-Year Period
title_full_unstemmed Onychomycosis in Northwestern Greece over a 7-Year Period
title_short Onychomycosis in Northwestern Greece over a 7-Year Period
title_sort onychomycosis in northwestern greece over a 7-year period
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603248/
https://www.ncbi.nlm.nih.gov/pubmed/33080905
http://dx.doi.org/10.3390/pathogens9100851
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