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Onychomycosis in Northwestern Greece over a 7-Year Period
Onychomycosis is considered as one of the major public health problems with a global distribution associated with geographic, demographic and environmental factors, underlying comorbidities and immunodeficiency disorders. This study was conducted to investigate the etiological agents of onychomycosi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603248/ https://www.ncbi.nlm.nih.gov/pubmed/33080905 http://dx.doi.org/10.3390/pathogens9100851 |
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author | Sakkas, Hercules Kittas, Christos Kapnisi, Georgia Priavali, Efthalia Kallinteri, Amalia Bassukas, Ioannis D. Gartzonika, Konstantina |
author_facet | Sakkas, Hercules Kittas, Christos Kapnisi, Georgia Priavali, Efthalia Kallinteri, Amalia Bassukas, Ioannis D. Gartzonika, Konstantina |
author_sort | Sakkas, Hercules |
collection | PubMed |
description | Onychomycosis is considered as one of the major public health problems with a global distribution associated with geographic, demographic and environmental factors, underlying comorbidities and immunodeficiency disorders. This study was conducted to investigate the etiological agents of onychomycosis, in Northwestern Greece during a 7-year period. The study population included 1095 outpatients with clinically suspected onychomycosis that presented to the University Hospital of Ioannina, NW Greece (2011–2017). Samples were examined for causative fungi, and mycological identification was established using standard mycological methods. Demographic data of each patient, comorbidities, localization of infection and history of previous fungal infection were collected. Onychomycosis was diagnosed in 317 of the 1095 suspected cases (28.9%) and the most frequently isolated pathogens were yeasts (50.8%) followed by dermatophytes (36.9%) and non-dermatophyte molds (NDMs) (12.3%). Dermatophytes were mostly involved in toenail onychomycosis (90.6%) and more commonly affected males than females (57.3% vs. 42.7%), while the predominantly isolated pathogen was Τrichophyton rubrum (74.4%) followed by Τrichophyton interdigitale (21.4%). Candida albicans was the most prevalent isolated yeast (82%), whereas among the cases with onychomycosis due to NDMs, Aspergillus spp. were isolated as the principal species (59%). Continuous monitoring should be performed in order to identify possible trends and shifts in species isolation rates and to evaluate the impact of onychomycosis among the general population and high-risk groups. |
format | Online Article Text |
id | pubmed-7603248 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76032482020-11-01 Onychomycosis in Northwestern Greece over a 7-Year Period Sakkas, Hercules Kittas, Christos Kapnisi, Georgia Priavali, Efthalia Kallinteri, Amalia Bassukas, Ioannis D. Gartzonika, Konstantina Pathogens Article Onychomycosis is considered as one of the major public health problems with a global distribution associated with geographic, demographic and environmental factors, underlying comorbidities and immunodeficiency disorders. This study was conducted to investigate the etiological agents of onychomycosis, in Northwestern Greece during a 7-year period. The study population included 1095 outpatients with clinically suspected onychomycosis that presented to the University Hospital of Ioannina, NW Greece (2011–2017). Samples were examined for causative fungi, and mycological identification was established using standard mycological methods. Demographic data of each patient, comorbidities, localization of infection and history of previous fungal infection were collected. Onychomycosis was diagnosed in 317 of the 1095 suspected cases (28.9%) and the most frequently isolated pathogens were yeasts (50.8%) followed by dermatophytes (36.9%) and non-dermatophyte molds (NDMs) (12.3%). Dermatophytes were mostly involved in toenail onychomycosis (90.6%) and more commonly affected males than females (57.3% vs. 42.7%), while the predominantly isolated pathogen was Τrichophyton rubrum (74.4%) followed by Τrichophyton interdigitale (21.4%). Candida albicans was the most prevalent isolated yeast (82%), whereas among the cases with onychomycosis due to NDMs, Aspergillus spp. were isolated as the principal species (59%). Continuous monitoring should be performed in order to identify possible trends and shifts in species isolation rates and to evaluate the impact of onychomycosis among the general population and high-risk groups. MDPI 2020-10-17 /pmc/articles/PMC7603248/ /pubmed/33080905 http://dx.doi.org/10.3390/pathogens9100851 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sakkas, Hercules Kittas, Christos Kapnisi, Georgia Priavali, Efthalia Kallinteri, Amalia Bassukas, Ioannis D. Gartzonika, Konstantina Onychomycosis in Northwestern Greece over a 7-Year Period |
title | Onychomycosis in Northwestern Greece over a 7-Year Period |
title_full | Onychomycosis in Northwestern Greece over a 7-Year Period |
title_fullStr | Onychomycosis in Northwestern Greece over a 7-Year Period |
title_full_unstemmed | Onychomycosis in Northwestern Greece over a 7-Year Period |
title_short | Onychomycosis in Northwestern Greece over a 7-Year Period |
title_sort | onychomycosis in northwestern greece over a 7-year period |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603248/ https://www.ncbi.nlm.nih.gov/pubmed/33080905 http://dx.doi.org/10.3390/pathogens9100851 |
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