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Prognostic significance of a normal karyotype in adult patients with BCR-ABL1-positive acute lymphoblastic leukemia in the tyrosine kinase inhibitor era

OBJECTIVE: The occurrence of cryptic Philadelphia (Ph) chromosome translocation is rare in BCR-ABL1-positive acute lymphoblastic leukemia (BCR-ABL1(+) ALL) and is of unknown significance in the tyrosine kinase inhibitor (TKI) era. METHODS: We retrospectively studied a series of adult patients receiv...

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Detalles Bibliográficos
Autores principales: Shi, Ting, Wang, Huanping, Xie, Mixue, Li, Xueying, Zhu, Lixia, Ye, Xiujin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603291/
https://www.ncbi.nlm.nih.gov/pubmed/33206758
http://dx.doi.org/10.6061/clinics/2020/e2011