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Reduced monoaminergic nuclei MRI signal detectable in pre-symptomatic older adults with future memory decline
Evidence from murine models and human post-mortem studies indicates that monoaminergic nuclei undergo degeneration at the pre-symptomatic stage of Alzheimer’s disease (AD). Analysing 129 datasets from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and relying on the Clinical Dementia Rating...
Autores principales: | Venneri, Annalena, De Marco, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603335/ https://www.ncbi.nlm.nih.gov/pubmed/33127923 http://dx.doi.org/10.1038/s41598-020-71368-1 |
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