Cargando…

Marcksl1 modulates endothelial cell mechanoresponse to haemodynamic forces to control blood vessel shape and size

The formation of vascular tubes is driven by extensive changes in endothelial cell (EC) shape. Here, we have identified a role of the actin-binding protein, Marcksl1, in modulating the mechanical properties of EC cortex to regulate cell shape and vessel structure during angiogenesis. Increasing and...

Descripción completa

Detalles Bibliográficos
Autores principales: Kondrychyn, Igor, Kelly, Douglas J., Carretero, Núria Taberner, Nomori, Akane, Kato, Kagayaki, Chong, Jeronica, Nakajima, Hiroyuki, Okuda, Satoru, Mochizuki, Naoki, Phng, Li-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603353/
https://www.ncbi.nlm.nih.gov/pubmed/33127887
http://dx.doi.org/10.1038/s41467-020-19308-5