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Marcksl1 modulates endothelial cell mechanoresponse to haemodynamic forces to control blood vessel shape and size
The formation of vascular tubes is driven by extensive changes in endothelial cell (EC) shape. Here, we have identified a role of the actin-binding protein, Marcksl1, in modulating the mechanical properties of EC cortex to regulate cell shape and vessel structure during angiogenesis. Increasing and...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603353/ https://www.ncbi.nlm.nih.gov/pubmed/33127887 http://dx.doi.org/10.1038/s41467-020-19308-5 |