Cargando…

Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting

Activity-dependent neuroprotective protein (ADNP) mutations are linked with cognitive dysfunctions characterizing the autistic-like ADNP syndrome patients, who also suffer from delayed motor maturation. We thus hypothesized that ADNP is deregulated in versatile myopathies and that local ADNP muscle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kapitansky, Oxana, Karmon, Gidon, Sragovich, Shlomo, Hadar, Adva, Shahoha, Meishar, Jaljuli, Iman, Bikovski, Lior, Giladi, Eliezer, Palovics, Robert, Iram, Tal, Gozes, Illana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603382/ https://www.ncbi.nlm.nih.gov/pubmed/33086621 http://dx.doi.org/10.3390/cells9102320

Ejemplares similares

Age and Sex-Dependent ADNP Regulation of Muscle Gene Expression Is Correlated with Motor Behavior: Possible Feedback Mechanism with PACAP
por: Kapitansky, Oxana, et al.
Publicado: (2020)

Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond
por: Kapitansky, Oxana, et al.
Publicado: (2020)

The autism/neuroprotection-linked ADNP/NAP regulate the excitatory glutamatergic synapse
por: Sragovich, Shlomo, et al.
Publicado: (2019)

VIP/PACAP-Based Drug Development: The ADNP/NAP-Derived Mirror Peptides SKIP and D-SKIP Exhibit Distinctive in vivo and in silico Effects
por: Sragovich, Shlomo, et al.
Publicado: (2020)

Discovery of autism/intellectual disability somatic mutations in Alzheimer's brains: mutated ADNP cytoskeletal impairments and repair as a case study
por: Ivashko-Pachima, Yanina, et al.
Publicado: (2019)

Distinct Impairments Characterizing Different ADNP Mutants Reveal Aberrant Cytoplasmic-Nuclear Crosstalk
por: Ganaiem, Maram, et al.
Publicado: (2022)

The autism-mutated ADNP plays a key role in stress response
por: Sragovich, Shlomo, et al.
Publicado: (2019)

NAP (Davunetide): The Neuroprotective ADNP Drug Candidate Penetrates Cell Nuclei Explaining Pleiotropic Mechanisms
por: Ganaiem, Maram, et al.
Publicado: (2023)

Cellular and animal models of skin alterations in the autism-related ADNP syndrome
por: Mollinedo, Pilar, et al.
Publicado: (2019)

ADNP Regulates Cognition: A Multitasking Protein
por: Gozes, Illana
Publicado: (2018)

Novel Marker for the Onset of Frontotemporal Dementia: Early Increase in Activity-Dependent Neuroprotective Protein (ADNP) in the Face of Tau Mutation
por: Schirer, Yulie, et al.
Publicado: (2014)

The ADNP Syndrome and CP201 (NAP) Potential and Hope
por: Gozes, Illana
Publicado: (2020)

Neuropeptide GPCRs in neuroendocrinology: the case of activity-dependent neuroprotective protein (ADNP)
por: Gozes, Illana
Publicado: (2012)

Activity-dependent neuroprotective protein (ADNP): from autism to Alzheimer’s disease
por: Gozes, Illana
Publicado: (2015)

ADNP: in search for molecular mechanisms and innovative therapeutic strategies for frontotemporal degeneration
por: Gozes, Illana, et al.
Publicado: (2015)

STOP Codon Mutations at Sites of Natural Caspase Cleavage Are Implicated in Autism and Alzheimer’s Disease: The Case of ADNP
por: Gozes, Illana, et al.
Publicado: (2022)

Preventive, personalized medicine at the level of key regulatory proteins: updates on activity-dependent neuroprotective protein (ADNP) as a case study
por: Gozes, Illana
Publicado: (2014)

Risperidone and NAP protect cognition and normalize gene expression in a schizophrenia mouse model
por: Vaisburd, Sinaya, et al.
Publicado: (2015)

The ADNP Derived Peptide, NAP Modulates the Tubulin Pool: Implication for Neurotrophic and Neuroprotective Activities
por: Oz, Saar, et al.
Publicado: (2012)

Premature primary tooth eruption in cognitive/motor-delayed ADNP-mutated children
por: Gozes, I, et al.
Publicado: (2017)

Premature primary tooth eruption in cognitive/motor-delayed ADNP-mutated children
por: Gozes, I, et al.
Publicado: (2017)

ADNP, a Microtubule Interacting Protein, Provides Neuroprotection Through End Binding Proteins and Tau: An Amplifier Effect
por: Gozes, Illana, et al.
Publicado: (2018)

A multi-lab experimental assessment reveals that replicability can be improved by using empirical estimates of genotype-by-lab interaction
por: Jaljuli, Iman, et al.
Publicado: (2023)

Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies
por: Malishkevich, A, et al.
Publicado: (2015)

Chromatin remodeler Activity-Dependent Neuroprotective Protein (ADNP) contributes to syndromic autism
por: D’Incal, Claudio Peter, et al.
Publicado: (2023)

cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal
por: Shahoha, Meishar, et al.
Publicado: (2022)

Anti-inflammatory Effects of the Octapeptide NAP in Human Microbiota-Associated Mice Suffering from Subacute Ileitis
por: Escher, Ulrike, et al.
Publicado: (2018)

Higher ATM expression in lymphoblastoid cell lines from centenarian compared with younger women
por: Hadar, Adva, et al.
Publicado: (2022)

Surgery duration: Optimized prediction and causality analysis
por: Babayoff, Orel, et al.
Publicado: (2022)

Immune-modulatory Properties of the Octapeptide NAP in Campylobacter jejuni Infected Mice Suffering from Acute Enterocolitis
por: Heimesaat, Markus M., et al.
Publicado: (2020)

Therapeutic Potential of Vasoactive Intestinal Peptide and its Derivative Stearyl-Norleucine-VIP in Inflammation-Induced Osteolysis
por: Eger, Michal, et al.
Publicado: (2021)

Tau pathology: predictive diagnostics, targeted preventive and personalized medicine and application of advanced research in medical practice
por: Gozes, Illana
Publicado: (2010)

ADNP Syndrome: A Qualitative Assessment of Symptoms, Therapies, and Challenges
por: Fastman, Jarrett, et al.
Publicado: (2023)

ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling
por: Sun, Xiaoyun, et al.
Publicado: (2020)

Activity-Dependent Neuroprotective Protein (ADNP): An Overview of Its Role in the Eye
por: Maugeri, Grazia, et al.
Publicado: (2022)

ADNP is associated with immune infiltration and radiosensitivity in hepatocellular carcinoma for predicting the prognosis
por: Wang, Xuan, et al.
Publicado: (2023)

A Novel Microtubule-Tau Association Enhancer and Neuroprotective Drug Candidate: Ac-SKIP
por: Ivashko-Pachima, Yanina, et al.
Publicado: (2019)

Corrigendum: A Novel Microtubule-Tau Association Enhancer and Neuroprotective Drug Candidate: Ac-SKIP
por: Ivashko-Pachima, Yanina, et al.
Publicado: (2021)

ADNP Upregulation Promotes Bladder Cancer Cell Proliferation via the AKT Pathway
por: Zhu, Shuai, et al.
Publicado: (2020)

NAP and D-SAL: neuroprotection against the β amyloid peptide (1–42)
por: Gozes, Illana, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_p2l4bkhusqkrgq2fambpo1k907