Cargando…
Handling deviating control values in concentration-response curves
In cell biology, pharmacology and toxicology dose-response and concentration-response curves are frequently fitted to data with statistical methods. Such fits are used to derive quantitative measures (e.g. EC[Formula: see text] values) describing the relationship between the concentration of a compo...
Autores principales: | Kappenberg, Franziska, Brecklinghaus, Tim, Albrecht, Wiebke, Blum, Jonathan, van der Wurp, Carola, Leist, Marcel, Hengstler, Jan G., Rahnenführer, Jörg |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603474/ https://www.ncbi.nlm.nih.gov/pubmed/32965549 http://dx.doi.org/10.1007/s00204-020-02913-0 |
Ejemplares similares
-
Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review
por: Kappenberg, Franziska, et al.
Publicado: (2023) -
Comparison of observation-based and model-based identification of alert concentrations from concentration–expression data
por: Kappenberg, Franziska, et al.
Publicado: (2021) -
Information sharing in high-dimensional gene expression data for improved parameter estimation in concentration-response modelling
por: Kappenberg, Franziska, et al.
Publicado: (2023) -
Structure-based virtual screening of CYP1A1 inhibitors: towards rapid tier-one assessment of potential developmental toxicants
por: Goh, Janice Jia Ni, et al.
Publicado: (2021) -
The use of Bayesian methodology in the development and validation of a tiered assessment approach towards prediction of rat acute oral toxicity
por: Firman, James W., et al.
Publicado: (2022)