Crbn modulates calcium influx by regulating Orai1 during efferocytosis

Calcium flux regulating intracellular calcium levels is essential and modulated for efficient efferocytosis. However, the molecular mechanism by which calcium flux is modulated during efferocytosis remains elusive. Here, we report that Orai1, a Crbn substrate, is upregulated via its attenuated inter...

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Detalles Bibliográficos
Autores principales: Moon, Hyunji, Min, Chanhyuk, Kim, Gayoung, Kim, Deokhwan, Kim, Kwanhyeong, Lee, Sang-Ah, Moon, Byeongjin, Yang, Susumin, Lee, Juyeon, Yang, Seung-Joo, Cho, Steve K., Lee, Gwangrog, Lee, Chang Sup, Park, Chul-Seung, Park, Daeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603501/
https://www.ncbi.nlm.nih.gov/pubmed/33127885
http://dx.doi.org/10.1038/s41467-020-19272-0

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