Cargando…

A Computational Model of the Brain Cortex and Its Synchronization

Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortical model using Python language using the Brian sim...

Descripción completa

Detalles Bibliográficos
Autor principal: Kbah, Sadeem Nabeel Saleem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603543/
https://www.ncbi.nlm.nih.gov/pubmed/33150173
http://dx.doi.org/10.1155/2020/3874626
_version_ 1783603946003103744
author Kbah, Sadeem Nabeel Saleem
author_facet Kbah, Sadeem Nabeel Saleem
author_sort Kbah, Sadeem Nabeel Saleem
collection PubMed
description Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortical model using Python language using the Brian simulator. The Brian simulator is specialized in simulating the neuronal connections and synaptic interconnections. The dynamic connection model has multiple parameters in order to ensure an accurate simulation (Bowman, 2016). We concentrated on the connection weights and studied their effect on the interactivity and connectivity of the cortical neurons in the same cortical layer and across multiple layers. As synchronization helps us to measure the degree of correlation between two or more neuronal groups, the synchronization between the neuronal groups, which are connected across layers, is considered. Despite its obvious importance, there are no sufficient studies concerned about the synchronization in the simulated cortical models. Such studies can help in examining the hypothesis and the dynamical behavior of the simulated model. In this paper, we simulated a cortical model and dynamical behavior and then studied the effect of input noise on its internal neuronal networks and their synchronization.
format Online
Article
Text
id pubmed-7603543
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-76035432020-11-03 A Computational Model of the Brain Cortex and Its Synchronization Kbah, Sadeem Nabeel Saleem Biomed Res Int Research Article Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortical model using Python language using the Brian simulator. The Brian simulator is specialized in simulating the neuronal connections and synaptic interconnections. The dynamic connection model has multiple parameters in order to ensure an accurate simulation (Bowman, 2016). We concentrated on the connection weights and studied their effect on the interactivity and connectivity of the cortical neurons in the same cortical layer and across multiple layers. As synchronization helps us to measure the degree of correlation between two or more neuronal groups, the synchronization between the neuronal groups, which are connected across layers, is considered. Despite its obvious importance, there are no sufficient studies concerned about the synchronization in the simulated cortical models. Such studies can help in examining the hypothesis and the dynamical behavior of the simulated model. In this paper, we simulated a cortical model and dynamical behavior and then studied the effect of input noise on its internal neuronal networks and their synchronization. Hindawi 2020-10-23 /pmc/articles/PMC7603543/ /pubmed/33150173 http://dx.doi.org/10.1155/2020/3874626 Text en Copyright © 2020 Sadeem Nabeel Saleem Kbah. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kbah, Sadeem Nabeel Saleem
A Computational Model of the Brain Cortex and Its Synchronization
title A Computational Model of the Brain Cortex and Its Synchronization
title_full A Computational Model of the Brain Cortex and Its Synchronization
title_fullStr A Computational Model of the Brain Cortex and Its Synchronization
title_full_unstemmed A Computational Model of the Brain Cortex and Its Synchronization
title_short A Computational Model of the Brain Cortex and Its Synchronization
title_sort computational model of the brain cortex and its synchronization
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603543/
https://www.ncbi.nlm.nih.gov/pubmed/33150173
http://dx.doi.org/10.1155/2020/3874626
work_keys_str_mv AT kbahsadeemnabeelsaleem acomputationalmodelofthebraincortexanditssynchronization
AT kbahsadeemnabeelsaleem computationalmodelofthebraincortexanditssynchronization