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A Computational Model of the Brain Cortex and Its Synchronization
Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortical model using Python language using the Brian sim...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603543/ https://www.ncbi.nlm.nih.gov/pubmed/33150173 http://dx.doi.org/10.1155/2020/3874626 |
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author | Kbah, Sadeem Nabeel Saleem |
author_facet | Kbah, Sadeem Nabeel Saleem |
author_sort | Kbah, Sadeem Nabeel Saleem |
collection | PubMed |
description | Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortical model using Python language using the Brian simulator. The Brian simulator is specialized in simulating the neuronal connections and synaptic interconnections. The dynamic connection model has multiple parameters in order to ensure an accurate simulation (Bowman, 2016). We concentrated on the connection weights and studied their effect on the interactivity and connectivity of the cortical neurons in the same cortical layer and across multiple layers. As synchronization helps us to measure the degree of correlation between two or more neuronal groups, the synchronization between the neuronal groups, which are connected across layers, is considered. Despite its obvious importance, there are no sufficient studies concerned about the synchronization in the simulated cortical models. Such studies can help in examining the hypothesis and the dynamical behavior of the simulated model. In this paper, we simulated a cortical model and dynamical behavior and then studied the effect of input noise on its internal neuronal networks and their synchronization. |
format | Online Article Text |
id | pubmed-7603543 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-76035432020-11-03 A Computational Model of the Brain Cortex and Its Synchronization Kbah, Sadeem Nabeel Saleem Biomed Res Int Research Article Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortical model using Python language using the Brian simulator. The Brian simulator is specialized in simulating the neuronal connections and synaptic interconnections. The dynamic connection model has multiple parameters in order to ensure an accurate simulation (Bowman, 2016). We concentrated on the connection weights and studied their effect on the interactivity and connectivity of the cortical neurons in the same cortical layer and across multiple layers. As synchronization helps us to measure the degree of correlation between two or more neuronal groups, the synchronization between the neuronal groups, which are connected across layers, is considered. Despite its obvious importance, there are no sufficient studies concerned about the synchronization in the simulated cortical models. Such studies can help in examining the hypothesis and the dynamical behavior of the simulated model. In this paper, we simulated a cortical model and dynamical behavior and then studied the effect of input noise on its internal neuronal networks and their synchronization. Hindawi 2020-10-23 /pmc/articles/PMC7603543/ /pubmed/33150173 http://dx.doi.org/10.1155/2020/3874626 Text en Copyright © 2020 Sadeem Nabeel Saleem Kbah. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Kbah, Sadeem Nabeel Saleem A Computational Model of the Brain Cortex and Its Synchronization |
title | A Computational Model of the Brain Cortex and Its Synchronization |
title_full | A Computational Model of the Brain Cortex and Its Synchronization |
title_fullStr | A Computational Model of the Brain Cortex and Its Synchronization |
title_full_unstemmed | A Computational Model of the Brain Cortex and Its Synchronization |
title_short | A Computational Model of the Brain Cortex and Its Synchronization |
title_sort | computational model of the brain cortex and its synchronization |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603543/ https://www.ncbi.nlm.nih.gov/pubmed/33150173 http://dx.doi.org/10.1155/2020/3874626 |
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