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Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-β pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Polymorphisms in the transforming growth factor-beta...

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Detalles Bibliográficos
Autores principales: Santiago, Rayra P., Figueiredo, Camylla V. B., Fiuza, Luciana M., Yahouédéhou, Sètondji C. M. A., Oliveira, Rodrigo M., Aleluia, Milena M., Carvalho, Suellen P., Fonseca, Cleverson A., Nascimento, Valma M. L., Rocha, Larissa C., Guarda, Caroline C., Gonçalves, Marilda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603616/
https://www.ncbi.nlm.nih.gov/pubmed/33149723
http://dx.doi.org/10.1155/2020/3185015