Cargando…

Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-β pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Polymorphisms in the transforming growth factor-beta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santiago, Rayra P., Figueiredo, Camylla V. B., Fiuza, Luciana M., Yahouédéhou, Sètondji C. M. A., Oliveira, Rodrigo M., Aleluia, Milena M., Carvalho, Suellen P., Fonseca, Cleverson A., Nascimento, Valma M. L., Rocha, Larissa C., Guarda, Caroline C., Gonçalves, Marilda S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603616/ https://www.ncbi.nlm.nih.gov/pubmed/33149723 http://dx.doi.org/10.1155/2020/3185015

Ejemplares similares

TGFBR3 Polymorphisms (rs1805110 and rs7526590) Are Associated with Laboratory Biomarkers and Clinical Manifestations in Sickle Cell Anemia
por: Santiago, Rayra Pereira, et al.
Publicado: (2020)

Hydroxyurea alters circulating monocyte subsets and dampens its inflammatory potential in sickle cell anemia patients
por: Guarda, Caroline C., et al.
Publicado: (2019)

Associations between TGF-β1 Levels and Markers of Hemolysis, Inflammation, and Tissue Remodeling in Pediatric Sickle Cell Patients
por: Santiago, Rayra P., et al.
Publicado: (2021)

Priapism in sickle cell disease: Associations between NOS3 and EDN1 genetic polymorphisms and laboratory biomarkers
por: Figueiredo, Camylla Vilas Boas, et al.
Publicado: (2021)

Sickle cell disease: A distinction of two most frequent genotypes (HbSS and HbSC)
por: da Guarda, Caroline Conceição, et al.
Publicado: (2020)

Investigation of Lipid Profile and Clinical Manifestations in SCA Children
por: da Guarda, Caroline Conceição, et al.
Publicado: (2020)

Hydroxyurea alters hematological, biochemical and inflammatory biomarkers in Brazilian children with SCA: Investigating associations with βS haplotype and α-thalassemia
por: Yahouédéhou, Sètondji Cocou Modeste Alexandre, et al.
Publicado: (2019)

Sickle Cell Anemia: Variants in the CYP2D6, CAT, and SLC14A1 Genes Are Associated With Improved Hydroxyurea Response
por: Yahouédéhou, Sètondji Cocou Modeste Alexandre, et al.
Publicado: (2020)

Genetic Polymorphisms Associated with Environmental Exposure to Polycyclic Derivatives in African Children
por: de Oliveira, Rodrigo Mota, et al.
Publicado: (2018)

Sickle Cell Anemia Patients in Use of Hydroxyurea: Association between Polymorphisms in Genes Encoding Metabolizing Drug Enzymes and Laboratory Parameters
por: Yahouédéhou, Sètondji Cocou Modeste Alexandre, et al.
Publicado: (2018)

Role of paraoxonase 1 activity and PON1 gene polymorphisms in sickle cell disease
por: Menezes, Joelma Figueiredo, et al.
Publicado: (2023)

Leg Ulcers in Sickle Cell Disease: A Multifactorial Analysis Highlights the Hemolytic Profile
por: Santos, Edvan do Carmo, et al.
Publicado: (2023)

A Description of the Hemolytic Component in Sickle Leg Ulcer: The Role of Circulating miR-199a-5p, miR-144, and miR-126
por: Santos, Edvan do Carmo, et al.
Publicado: (2022)

Effect of N(Epsilon)-(carboxymethyl)lysine on Laboratory Parameters and Its Association with β(S) Haplotype in Children with Sickle Cell Anemia
por: Ndidi, Uche Samuel, et al.
Publicado: (2019)

Nasopharyngeal and Oropharyngeal Colonization by Staphylococcus aureus and Streptococcus pneumoniae and Prognostic Markers in Children with Sickle Cell Disease from the Northeast of Brazil
por: Rocha, Larissa C., et al.
Publicado: (2017)

Evaluation of Alpha-1 Antitrypsin Levels and SERPINA1 Gene Polymorphisms in Sickle Cell Disease
por: Carvalho, Magda Oliveira Seixas, et al.
Publicado: (2017)

Association of classical markers and establishment of the dyslipidemic sub-phenotype of sickle cell anemia
por: Aleluia, Milena Magalhães, et al.
Publicado: (2017)

Association of laboratory markers and cerebral blood flow among sickle cell anemia children
por: Adanho, Corynne Stéphanie Ahouéfa, et al.
Publicado: (2022)

Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profiles
por: Aleluia, Milena Magalhães, et al.
Publicado: (2017)

Endothelial Nitric Oxide Synthase (−786T>C) and Endothelin-1 (5665G>T) Gene Polymorphisms as Vascular Dysfunction Risk Factors in Sickle Cell Anemia
por: Vilas-Boas, Wendell, et al.
Publicado: (2016)

Effectiveness of Pharmacokinetic-Guided Hydroxyurea Dose Individualization in Patients with Sickle Cell Anemia: A Mini-Review
por: dos Santos Neres, Joelma Santana, et al.
Publicado: (2023)

Evaluation of Cardiometabolic Parameters among Obese Women Using Oral Contraceptives
por: Ferreira, Júnia Raquel Dutra, et al.
Publicado: (2017)

Laboratory and Genetic Biomarkers Associated with Cerebral Blood Flow Velocity in Hemoglobin SC Disease
por: Santiago, Rayra Pereira, et al.
Publicado: (2017)

Vaso‐occlusive crisis in a patient with sickle cell trait and COVID‐19
por: Freitas, Luiz A. R., et al.
Publicado: (2021)

Levels of high-density lipoprotein cholesterol (HDL-C) among children with steady-state sickle cell disease
por: Seixas, Magda O, et al.
Publicado: (2010)

Influence of βS-Globin Haplotypes and Hydroxyurea on Arginase I Levels in Sickle Cell Disease
por: Moreira, J. A., et al.
Publicado: (2016)

Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
por: de Almeida Oliveira, Dayse Cury, et al.
Publicado: (2014)

Association of the clinical profile and overall survival of pediatric patients with acute lymphoblastic leukemia
por: Correa, Bruno Terra, et al.
Publicado: (2023)

A phased SNP-based classification of sickle cell anemia HBB haplotypes
por: Shaikho, Elmutaz M., et al.
Publicado: (2017)

Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review
por: Miranda, Gustavo Marinho, et al.
Publicado: (2021)

Haplotype Map of Sickle Cell Anemia in Tunisia
por: Moumni, Imen, et al.
Publicado: (2014)

Comment on “Molecular analysis and association with clinical and laboratory manifestations in children with sickle cell anemia”()
por: Souza Goncalves, Marilda
Publicado: (2014)

Evaluation of 2D and 3D Erythroid Differentiation Protocols Using Sickle Cell Disease and Healthy Donor Induced Pluripotent Stem Cells
por: Martins, Gabriele Louise Soares, et al.
Publicado: (2023)

Frequency of beta S globin gene haplotypes among sickle cell patients in Nigeria
por: Adabale, Abosede, et al.
Publicado: (2021)

Sickle cell anemia: clinical diversity and beta S-globin haplotypes
por: Loggetto, Sandra Regina
Publicado: (2013)

Kidney dysfunction and beta S-haplotypes in patients with sickle cell disease
por: Rocha, Lilianne Brito da Silva, et al.
Publicado: (2013)

Experimental Generation of SNP Haplotype Signatures in Patients with Sickle Cell Anaemia
por: Menzel, Stephan, et al.
Publicado: (2010)

The origin of HTLV-1 in the South Bahia by phylogenetic, mitochondrial DNA and β-globin analysis
por: Gadelha, Sandra R, et al.
Publicado: (2014)

Interfamilial transmission of HTLV-1 in the South of Bahia, Brazil
por: Gadelha, Sandra R, et al.
Publicado: (2014)

Classical sickle beta-globin haplotypes exhibit a high degree of long-range haplotype similarity in African and Afro-Caribbean populations
por: Hanchard, Neil, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_1q6ok9u96ovdrjsa36h505inp9