Cargando…
Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer
A hypoxic microenvironment is a hallmark in different types of tumors; this phenomenon participates in a metabolic alteration that confers resistance to treatments. Because of this, it was proposed that a combination of 2-methoxyestradiol (2-ME) and sodium dichloroacetate (DCA) could reduce this alt...
Autores principales: | Romero, Yair, Castillejos-López, Manuel, Romero-García, Susana, Aguayo, Alfonso Salgado, Herrera, Iliana, Garcia-Martin, Misael O., Torres-Espíndola, Luz Maria, Negrete-García, Maria Cristina, Olvera, Angel Camarena, Huerta-Cruz, Juan Carlos, Velázquez-Cruz, Rafael, Cisneros, José, Soto, Edgar Flores, Solís-Chagoyán, Héctor, Mendoza-Milla, Criselda, Cabello-Gutiérrez, Carlos, Ruiz, Víctor, Aquino-Gálvez, Arnoldo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603622/ https://www.ncbi.nlm.nih.gov/pubmed/33149807 http://dx.doi.org/10.1155/2020/3176375 |
Ejemplares similares
-
Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia
por: AQUINO-GÁLVEZ, ARNOLDO, et al.
Publicado: (2016) -
Functional Repercussions of Hypoxia-Inducible Factor-2α in Idiopathic Pulmonary Fibrosis
por: Torres-Soria, Ana Karen, et al.
Publicado: (2022) -
Dysregulated expression of hypoxia-inducible factors augments myofibroblasts differentiation in idiopathic pulmonary fibrosis
por: Aquino-Gálvez, Arnoldo, et al.
Publicado: (2019) -
Ivermectin: A Controversial Focal Point during the COVID-19 Pandemic
por: Castillejos-López, Manuel, et al.
Publicado: (2022) -
Hypoxia in Cancer and Fibrosis: Part of the Problem and Part of the Solution
por: Romero, Yair, et al.
Publicado: (2021)