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Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia

BACKGROUND: Glaucoma is a chronic optic nerve disease, often asymptomatic in an early stage, which is usually associated with elevated intraocular pressure. Good adherence to ocular hypotensive agents is essential to control the intraocular pressure and optic nerve damage. There is limited informati...

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Autores principales: Assem, Abel Sinshaw, Fekadu, Sofonias Addis, Yigzaw, Amsal Ambaw, Nigussie, Zelalem Mehari, Achamyeleh, Anemaw Asrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603651/
https://www.ncbi.nlm.nih.gov/pubmed/33149714
http://dx.doi.org/10.2147/OPTO.S274850
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author Assem, Abel Sinshaw
Fekadu, Sofonias Addis
Yigzaw, Amsal Ambaw
Nigussie, Zelalem Mehari
Achamyeleh, Anemaw Asrat
author_facet Assem, Abel Sinshaw
Fekadu, Sofonias Addis
Yigzaw, Amsal Ambaw
Nigussie, Zelalem Mehari
Achamyeleh, Anemaw Asrat
author_sort Assem, Abel Sinshaw
collection PubMed
description BACKGROUND: Glaucoma is a chronic optic nerve disease, often asymptomatic in an early stage, which is usually associated with elevated intraocular pressure. Good adherence to ocular hypotensive agents is essential to control the intraocular pressure and optic nerve damage. There is limited information on glaucoma drug adherence and associated factors in Ethiopia, particularly in the study area. OBJECTIVE: To determine the level of glaucoma drug adherence and associated factors among adult glaucoma patients attending Felege Hiwot Specialized Hospital, Northwest Ethiopia, 2019. MATERIALS AND METHODS: A hospital-based cross-sectional study was conducted at Felege Hiwot specialized Hospital from March 2019 to May 2019. A systematic random sampling method was used to select 402 study participants. A structured questionnaire was prepared, and adherence was assessed by using self-report questions. The collected data were entered into Epi data version 4.2.2.1 and exported into Statistical Package for Social Science version 23 for analysis. Tables, graphs, frequency, mean, and standard deviation were used for descriptive statistics. Variables with a p-value of <0.2 in the bivariable logistic regression were entered in the multivariable logistic regression, and variables with a p-value of <0.05 under multivariable analysis were taken as statistically significant factors for glaucoma drug adherence. RESULTS: Among a total of 390 study participants, 212 (56.2%) were adherent to their topical medication. Early glaucoma (AOR=2.8: 95% CI =1.29–5.91), normal vision (AOR=1.9: 95% CI=1.15–3.09), urban residence (AOR=1.6: 95% CI=1.03–2.51), family support (AOR=1.7: 95% CI=1.06–2.76) and information from pharmacist (AOR=1.8: 95% CI=1.11–2.99) were significantly associated with adherence. CONCLUSION: The level of glaucoma drug adherence was 56.2% among patients attending Felege Hiwot Specialized Hospital. Early glaucoma, normal visual acuity, family support, information on medication from the pharmacist, and urban residence were positively associated with adherence.
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spelling pubmed-76036512020-11-03 Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia Assem, Abel Sinshaw Fekadu, Sofonias Addis Yigzaw, Amsal Ambaw Nigussie, Zelalem Mehari Achamyeleh, Anemaw Asrat Clin Optom (Auckl) Original Research BACKGROUND: Glaucoma is a chronic optic nerve disease, often asymptomatic in an early stage, which is usually associated with elevated intraocular pressure. Good adherence to ocular hypotensive agents is essential to control the intraocular pressure and optic nerve damage. There is limited information on glaucoma drug adherence and associated factors in Ethiopia, particularly in the study area. OBJECTIVE: To determine the level of glaucoma drug adherence and associated factors among adult glaucoma patients attending Felege Hiwot Specialized Hospital, Northwest Ethiopia, 2019. MATERIALS AND METHODS: A hospital-based cross-sectional study was conducted at Felege Hiwot specialized Hospital from March 2019 to May 2019. A systematic random sampling method was used to select 402 study participants. A structured questionnaire was prepared, and adherence was assessed by using self-report questions. The collected data were entered into Epi data version 4.2.2.1 and exported into Statistical Package for Social Science version 23 for analysis. Tables, graphs, frequency, mean, and standard deviation were used for descriptive statistics. Variables with a p-value of <0.2 in the bivariable logistic regression were entered in the multivariable logistic regression, and variables with a p-value of <0.05 under multivariable analysis were taken as statistically significant factors for glaucoma drug adherence. RESULTS: Among a total of 390 study participants, 212 (56.2%) were adherent to their topical medication. Early glaucoma (AOR=2.8: 95% CI =1.29–5.91), normal vision (AOR=1.9: 95% CI=1.15–3.09), urban residence (AOR=1.6: 95% CI=1.03–2.51), family support (AOR=1.7: 95% CI=1.06–2.76) and information from pharmacist (AOR=1.8: 95% CI=1.11–2.99) were significantly associated with adherence. CONCLUSION: The level of glaucoma drug adherence was 56.2% among patients attending Felege Hiwot Specialized Hospital. Early glaucoma, normal visual acuity, family support, information on medication from the pharmacist, and urban residence were positively associated with adherence. Dove 2020-10-27 /pmc/articles/PMC7603651/ /pubmed/33149714 http://dx.doi.org/10.2147/OPTO.S274850 Text en © 2020 Assem et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Assem, Abel Sinshaw
Fekadu, Sofonias Addis
Yigzaw, Amsal Ambaw
Nigussie, Zelalem Mehari
Achamyeleh, Anemaw Asrat
Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia
title Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia
title_full Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia
title_fullStr Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia
title_full_unstemmed Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia
title_short Level of Glaucoma Drug Adherence and Its Associated Factors Among Adult Glaucoma Patients Attending Felege Hiwot Specialized Hospital, Bahir Dar City, Northwest Ethiopia
title_sort level of glaucoma drug adherence and its associated factors among adult glaucoma patients attending felege hiwot specialized hospital, bahir dar city, northwest ethiopia
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603651/
https://www.ncbi.nlm.nih.gov/pubmed/33149714
http://dx.doi.org/10.2147/OPTO.S274850
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