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Improved cytokine–receptor interaction prediction by exploiting the negative sample space

BACKGROUND: Cytokines act by binding to specific receptors in the plasma membrane of target cells. Knowledge of cytokine–receptor interaction (CRI) is very important for understanding the pathogenesis of various human diseases—notably autoimmune, inflammatory and infectious diseases—and identifying...

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Detalles Bibliográficos
Autores principales: Nath, Abhigyan, Leier, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603689/
https://www.ncbi.nlm.nih.gov/pubmed/33129275
http://dx.doi.org/10.1186/s12859-020-03835-5