Exosomal LncRNA–NEAT1 derived from MIF-treated mesenchymal stem cells protected against doxorubicin-induced cardiac senescence through sponging miR-221-3p

BACKGROUND: The chemotherapy drug doxorubicin (Dox) is widely used for treating a variety of cancers. However, its high cardiotoxicity hampered its clinical use. Exosomes derived from stem cells showed a therapeutic effect against Dox-induced cardiomyopathy (DIC). Previous studies reported that exos...

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Detalles Bibliográficos
Autores principales: Zhuang, Lei, Xia, Wenzheng, Chen, Didi, Ye, Yijia, Hu, Tingting, Li, Shiting, Hou, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603694/
https://www.ncbi.nlm.nih.gov/pubmed/33129330
http://dx.doi.org/10.1186/s12951-020-00716-0

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