Characterization of WWOX expression and function in canine mast cell tumors and malignant mast cell lines

BACKGROUND: The WW domain-containing oxidoreductase (WWOX) tumor suppressor gene is frequently lost in a variety of solid and hematopoietic malignancies in humans. Dysregulation of WWOX has been implicated as playing a key role in tumor cell survival, DNA damage repair, and genomic stability. The pu...

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Detalles Bibliográficos
Autores principales: Makii, Rebecca, Cook, Hanna, Louke, Darian, Breitbach, Justin, Jennings, Ryan, Premanandan, Christopher, Green, Eric M., Fenger, Joelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603737/
https://www.ncbi.nlm.nih.gov/pubmed/33129329
http://dx.doi.org/10.1186/s12917-020-02638-3

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