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Poorly known aspects of flattening the curve of COVID-19

A negative correlation between the final ceiling of the logistic curve and its slope, established long time ago via a simulation study, motivated this closer look at flattening the curve of COVID-19. The diffusion of the virus is analyzed with S-shaped logistic-curve fits on the 25 countries most af...

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Detalles Bibliográficos
Autores principales: Debecker, Alain, Modis, Theodore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603980/
https://www.ncbi.nlm.nih.gov/pubmed/33162618
http://dx.doi.org/10.1016/j.techfore.2020.120432
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author Debecker, Alain
Modis, Theodore
author_facet Debecker, Alain
Modis, Theodore
author_sort Debecker, Alain
collection PubMed
description A negative correlation between the final ceiling of the logistic curve and its slope, established long time ago via a simulation study, motivated this closer look at flattening the curve of COVID-19. The diffusion of the virus is analyzed with S-shaped logistic-curve fits on the 25 countries most affected in which the curve was more than 95% completed at the time of the writing (mid-May 2020.) A negative correlation observed between the final number of infections and the slope of the logistic curve corroborates the result obtained long time ago via an extensive simulation study. There is both theoretical arguments and experimental evidence for the existence of such correlations. The flattening of the curve results in a retardation of the curve's midpoint, which entails an increase in the final number of infections. It is possible that more lives are lost at the end by this process. Our analysis also permits evaluation of the various governments’ interventions in terms of rapidity of response, efficiency of the actions taken (the amount of flattening achieved), and the number of days by which the curve was delayed. Not surprisingly, early decisive response—such as countrywide lockdown—proves to be the optimum strategy among the countries studied.
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spelling pubmed-76039802020-11-02 Poorly known aspects of flattening the curve of COVID-19 Debecker, Alain Modis, Theodore Technol Forecast Soc Change Article A negative correlation between the final ceiling of the logistic curve and its slope, established long time ago via a simulation study, motivated this closer look at flattening the curve of COVID-19. The diffusion of the virus is analyzed with S-shaped logistic-curve fits on the 25 countries most affected in which the curve was more than 95% completed at the time of the writing (mid-May 2020.) A negative correlation observed between the final number of infections and the slope of the logistic curve corroborates the result obtained long time ago via an extensive simulation study. There is both theoretical arguments and experimental evidence for the existence of such correlations. The flattening of the curve results in a retardation of the curve's midpoint, which entails an increase in the final number of infections. It is possible that more lives are lost at the end by this process. Our analysis also permits evaluation of the various governments’ interventions in terms of rapidity of response, efficiency of the actions taken (the amount of flattening achieved), and the number of days by which the curve was delayed. Not surprisingly, early decisive response—such as countrywide lockdown—proves to be the optimum strategy among the countries studied. Elsevier Inc. 2021-02 2020-10-31 /pmc/articles/PMC7603980/ /pubmed/33162618 http://dx.doi.org/10.1016/j.techfore.2020.120432 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Debecker, Alain
Modis, Theodore
Poorly known aspects of flattening the curve of COVID-19
title Poorly known aspects of flattening the curve of COVID-19
title_full Poorly known aspects of flattening the curve of COVID-19
title_fullStr Poorly known aspects of flattening the curve of COVID-19
title_full_unstemmed Poorly known aspects of flattening the curve of COVID-19
title_short Poorly known aspects of flattening the curve of COVID-19
title_sort poorly known aspects of flattening the curve of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603980/
https://www.ncbi.nlm.nih.gov/pubmed/33162618
http://dx.doi.org/10.1016/j.techfore.2020.120432
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