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Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

Tau protein (MAPT) is classified as a microtubule-associated protein (MAP) and is believed to regulate the axonal microtubule arrangement. It belongs to the tau/MAP2/MAP4 family of MAPs that have a similar microtubule binding region at their carboxy-terminal half. In tauopathies, such as Alzheimer&#...

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Detalles Bibliográficos
Autores principales: Brandt, Roland, Trushina, Nataliya I., Bakota, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604284/
https://www.ncbi.nlm.nih.gov/pubmed/33193056
http://dx.doi.org/10.3389/fneur.2020.590059